8JYI

Crystal structure of engineered HIV-1 Reverse Transcriptase RNase H domain complexed with laccaic acid E

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Pol protein,Pol protein,Ribonuclease H	polymer	151	16832.3	1	UniProt (A0A059PIR4) UniProt (A0A1D9J5E8) Pfam (PF00075) UniProt (by SIFTS) (P04585) In PDB	HIV-1 06TG.HT008
2	A	MANGANESE (II) ION	non-polymer		54.9	2	Chemie (MN)
3	A	7-[5-(2-azanylethyl)-2-oxidanyl-phenyl]-3,5,6,8-tetrakis(oxidanyl)-9,10-bis(oxidanylidene)anthracene-1,2-dicarboxylic acid	non-polymer		495.4	1	Chemie (V9O)
4	A	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
5		water	water		18.0	26	Chemie (HOH)

Sequence modifications

A: 7 - 86 (UniProt: A0A059PIR4)

PDB	External Database	Details
Gly 1	-	expression tag
Pro 2	-	expression tag
Gly 3	-	expression tag
Gly 4	-	expression tag
Ser 5	-	expression tag
Met 6	-	expression tag

A: 87 - 106 (PDB: 8JYI)
A: 107 - 151 (UniProt: A0A1D9J5E8)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	16832.3
Non-Polymers*	Number of molecules	5
	Total formula weight	736.1
All*	Total formula weight	17568.4

*Water molecules are not included.