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8JYI

Crystal structure of engineered HIV-1 Reverse Transcriptase RNase H domain complexed with laccaic acid E

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1APol protein,Pol protein,Ribonuclease Hpolymer15116832.31UniProt (A0A059PIR4)
UniProt (A0A1D9J5E8)
Pfam (PF00075)
UniProt (by SIFTS) (P04585)
In PDB
HIV-1 06TG.HT008
2AMANGANESE (II) IONnon-polymer54.92Chemie (MN)
3A7-[5-(2-azanylethyl)-2-oxidanyl-phenyl]-3,5,6,8-tetrakis(oxidanyl)-9,10-bis(oxidanylidene)anthracene-1,2-dicarboxylic acidnon-polymer495.41Chemie (V9O)
4AZINC IONnon-polymer65.42Chemie (ZN)
5waterwater18.026Chemie (HOH)
Sequence modifications
A: 7 - 86 (UniProt: A0A059PIR4)
PDBExternal DatabaseDetails
Gly 1-expression tag
Pro 2-expression tag
Gly 3-expression tag
Gly 4-expression tag
Ser 5-expression tag
Met 6-expression tag
A: 87 - 106 (PDB: 8JYI)
A: 107 - 151 (UniProt: A0A1D9J5E8)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight16832.3
Non-Polymers*Number of molecules5
Total formula weight736.1
All*Total formula weight17568.4
*Water molecules are not included.

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PDB entries from 2024-06-12

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