8JYE

Crystal Structure of Intracellular B30.2 Domain of BTN3A1 and BTN2A1 in Complex with HMBPP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Butyrophilin subfamily 2 member A1	polymer	218	24676.9	2	UniProt (Q7KYR7) Pfam (PF13765) Pfam (PF00622)	Homo sapiens (human)
2	C, D (C, D)	Butyrophilin subfamily 3 member A1	polymer	196	22661.8	2	UniProt (O00481) Pfam (PF13765) Pfam (PF00622)	Homo sapiens (human)
3	E, F, H, I (A, B)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	4	Chemie (PEG)
4	G, J, K, L (A, B, C)	1,2-ETHANEDIOL	non-polymer		62.1	4	Chemie (EDO)
5	M (C)	PENTAETHYLENE GLYCOL	non-polymer		238.3	1	Chemie (1PE)
6	N (C)	TRIETHYLENE GLYCOL	non-polymer		150.2	1	Chemie (PGE)
7	O, P (C, D)	(2E)-4-hydroxy-3-methylbut-2-en-1-yl trihydrogen diphosphate	non-polymer		262.1	2	Chemie (H6P)
8	Q, R, S, T (A, B, C, D)	water	water		18.0	394	Chemie (HOH)

Sequence modifications

A, B: 316 - 527 (UniProt: Q7KYR7)

PDB	External Database	Details
Gly 310	-	expression tag
Ala 311	-	expression tag
Gly 312	-	expression tag
Ala 313	-	expression tag
Gly 314	-	expression tag
Ala 315	-	expression tag

C, D: 298 - 483 (UniProt: O00481)

PDB	External Database	Details
Met 296	-	expression tag
Gly 297	-	expression tag
Leu 484	-	expression tag
Glu 485	-	expression tag
His 486	-	expression tag
His 487	-	expression tag
His 488	-	expression tag
His 489	-	expression tag
His 490	-	expression tag
His 491	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	94677.3
Non-Polymers*	Number of molecules	12
	Total formula weight	1585.4
All*	Total formula weight	96262.7

*Water molecules are not included.