8JY6
Structure of TbAQP2 in complex with anti-trypanosomatid drug melarsoprol
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Aquaglyceroporin 2 | polymer | 343 | 36775.9 | 4 | UniProt (Q6ZXT3) Pfam (PF00230) In PDB | Trypanosoma brucei brucei | |
2 | A, B, C, D | [(4~{R})-2-[4-[[4,6-bis(azanyl)-1,3,5-triazin-2-yl]amino]phenyl]-1,3,2-dithiarsolan-4-yl]methanol | non-polymer | 398.3 | 4 | Chemie (L1U) |
Sequence modifications
A, B, C, D: 1 - 312 (UniProt: Q6ZXT3)
PDB | External Database | Details |
---|---|---|
Ser 313 | - | expression tag |
Asn 314 | - | expression tag |
Ser 315 | - | expression tag |
Trp 316 | - | expression tag |
Ser 317 | - | expression tag |
His 318 | - | expression tag |
Pro 319 | - | expression tag |
Gln 320 | - | expression tag |
Phe 321 | - | expression tag |
Glu 322 | - | expression tag |
Lys 323 | - | expression tag |
Gly 324 | - | expression tag |
Gly 325 | - | expression tag |
Gly 326 | - | expression tag |
Ser 327 | - | expression tag |
Gly 328 | - | expression tag |
Gly 329 | - | expression tag |
Gly 330 | - | expression tag |
Ser 331 | - | expression tag |
Gly 332 | - | expression tag |
Gly 333 | - | expression tag |
Ser 334 | - | expression tag |
Ala 335 | - | expression tag |
Trp 336 | - | expression tag |
Ser 337 | - | expression tag |
His 338 | - | expression tag |
Pro 339 | - | expression tag |
Gln 340 | - | expression tag |
Phe 341 | - | expression tag |
Glu 342 | - | expression tag |
Lys 343 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 147103.7 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1593.4 | |
All* | Total formula weight | 148697.0 |