8JY0
Crystal structure of RhoBAST complexed with TMR-DN
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, D (A, C, E) | U1 small nuclear ribonucleoprotein A | polymer | 102 | 11744.8 | 3 | UniProt (M0R2B8) Pfam (PF00076) UniProt (by SIFTS) (P09012) | Homo sapiens (human) | |
| 2 | B, E, F (B, D, F) | RhoBAST | polymer | 64 | 20609.3 | 3 | artificial sequences | ||
| 3 | G, H, M, N (B, D) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) PubChem (888) | |||
| 4 | I, P, R (B, D, F) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 3 | Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537) | |||
| 5 | J (B) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
| 6 | K, O, Q (B, D, F) | 5-aminocarbonyl-2-[3-(dimethylamino)-6-dimethylazaniumylidene-xanthen-9-yl]benzoate | non-polymer | 429.5 | 3 | Chemie (V8C) | |||
| 7 | L (B) | 2,4-dinitroaniline | non-polymer | 183.1 | 1 | Chemie (V7U) PubChem (7321) | |||
| 8 | S, T, U, V, W... (A, B, C, E, D...) | water | water | 18.0 | 97 | Chemie (HOH) |
Sequence modifications
A, C, E: 2 - 102 (UniProt: M0R2B8)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| His 31 | Tyr 31 | engineered mutation |
| Arg 36 | Gln 36 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 97062.3 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 3048.5 | |
| All* | Total formula weight | 100110.8 |
