8JUG
Crystal structure of human MMP-7 in complex with inhibitor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Matrilysin | polymer | 175 | 19344.7 | 1 | UniProt (P09237) Pfam (PF00413) In PDB | Homo sapiens (human) | Matrin,Matrix metalloproteinase-7,MMP-7,Pump-1 protease,Uterine metalloproteinase |
2 | C | Peptide Inhibitor | polymer | 7 | 938.4 | 1 | synthetic construct | ||
3 | A | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
4 | A | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
5 | water | water | 18.0 | 113 | Chemie (HOH) |
Sequence modifications
A: 95 - 267 (UniProt: P09237)
PDB | External Database | Details |
---|---|---|
Met 93 | - | initiating methionine |
Gly 94 | - | expression tag |
Gln 215 | Glu 215 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 20283.2 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 211.0 | |
All* | Total formula weight | 20494.1 |