8JUC
Identification of small-molecule binding sites of a ubiquitin-conjugating enzyme-UBE2T through fragment-based screening
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Ubiquitin-conjugating enzyme E2 T | polymer | 156 | 17830.6 | 1 | UniProt (Q9NPD8) Pfam (PF00179) | Homo sapiens (human) | E2 ubiquitin-conjugating enzyme T,Ubiquitin carrier protein T,Ubiquitin-protein ligase T |
| 2 | B (A) | 7-methyl-2-(trifluoromethyl)-3~{H}-[1,2,4]triazolo[1,5-a]pyridin-5-one | non-polymer | 217.1 | 1 | Chemie (V23) | |||
| 3 | C, D (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 4 | E (A) | water | water | 18.0 | 113 | Chemie (HOH) |
Sequence modifications
A: 1 - 154 (UniProt: Q9NPD8)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 17830.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 341.3 | |
| All* | Total formula weight | 18171.9 |
