8JU0
hOCT1 in complex with spironolactone in inward facing occluded conformation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Solute carrier family 22 member 1 | polymer | 566 | 62569.2 | 1 | UniProt (O15245) Pfam (PF00083) | Homo sapiens (human) | Organic cation transporter 1,hOCT1 |
| 2 | B (A) | SPIRONOLACTONE | non-polymer | 416.6 | 1 | Chemie (SNL) PubChem (16757735) PubChem (18594034) PubChem (5267) PubChem (24867532) PubChem (24884066) PubChem (16394537) PubChem (44268286) PubChem (44280002) PubChem (1742267) PubChem (1742266) PubChem (50937095) PubChem (53316433) PubChem (54670637) PubChem (58649021) PubChem (59078570) PubChem (59106600) PubChem (60108251) PubChem (60113353) PubChem (53485777) PubChem (73896881) PubChem (76974557) PubChem (59105084) PubChem (941624) PubChem (89555390) PubChem (5833) PubChem (90660429) PubChem (1255733) PubChem (1425524) PubChem (117072388) PubChem (7058140) PubChem (124303478) PubChem (124304402) PubChem (6093165) PubChem (124900200) PubChem (6419955) PubChem (6432512) PubChem (129010254) PubChem (6604008) PubChem (6604182) PubChem (6710654) PubChem (100923457) PubChem (7061088) PubChem (7061090) PubChem (11869579) PubChem (122680945) PubChem (10477021) PubChem (138756141) PubChem (124304445) PubChem (11509929) PubChem (11863525) PubChem (11869418) PubChem (11869419) PubChem (11869420) PubChem (11869578) PubChem (11869580) PubChem (11957686) PubChem (124746581) PubChem (12358364) PubChem (124900199) PubChem (129009897) PubChem (131698401) PubChem (139421976) PubChem (154731467) |
Sequence modifications
A: 1 - 554 (UniProt: O15245)
| PDB | External Database | Details |
|---|---|---|
| Glu 555 | - | expression tag |
| Asp 556 | - | expression tag |
| Gln 557 | - | expression tag |
| Val 558 | - | expression tag |
| Asp 559 | - | expression tag |
| Pro 560 | - | expression tag |
| Arg 561 | - | expression tag |
| Leu 562 | - | expression tag |
| Ile 563 | - | expression tag |
| Asp 564 | - | expression tag |
| Gly 565 | - | expression tag |
| Lys 566 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 62569.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 416.6 | |
| All* | Total formula weight | 62985.7 |
