8JTS
hOCT1 in complex with metformin in outward open conformation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Solute carrier family 22 member 1 | polymer | 566 | 62569.2 | 1 | UniProt (O15245) Pfam (PF00083) In PDB | Homo sapiens (human) | Organic cation transporter 1,hOCT1 |
| 2 | A | Metformin | non-polymer | 129.2 | 1 | Chemie (MF8) |
Sequence modifications
A: 1 - 554 (UniProt: O15245)
| PDB | External Database | Details |
|---|---|---|
| Glu 555 | - | expression tag |
| Asp 556 | - | expression tag |
| Gln 557 | - | expression tag |
| Val 558 | - | expression tag |
| Asp 559 | - | expression tag |
| Pro 560 | - | expression tag |
| Arg 561 | - | expression tag |
| Leu 562 | - | expression tag |
| Ile 563 | - | expression tag |
| Asp 564 | - | expression tag |
| Gly 565 | - | expression tag |
| Lys 566 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 62569.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 129.2 | |
| All* | Total formula weight | 62698.3 |
