8JT0

Dihydrofolate reductase-like enzyme from Leptospira interrogans with additional NADP+

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	Dihydrofolate reductase family protein	polymer	203	22607.7	10	UniProt (A0A8I0PU34) UniProt (by SIFTS) (A0AA40WBR8) In PDB	Leptospira interrogans serovar Pomona
2	H, I, E, A, F...	PENTAETHYLENE GLYCOL	non-polymer		238.3	15	Chemie (1PE)
3	H, I, E, A, F...	NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		743.4	10	Chemie (NAP)
4	D, H, I, E, A...	SULFATE ION	non-polymer		96.1	34	Chemie (SO4)
5	I, G, D	ACETATE ION	non-polymer		59.0	3	Chemie (ACT)
6		water	water		18.0	725	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H, I, J: 1 - 197 (UniProt: A0A8I0PU34)

PDB	External Database	Details
His 198	-	expression tag
His 199	-	expression tag
His 200	-	expression tag
His 201	-	expression tag
His 202	-	expression tag
His 203	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	10
	Total formula weight	226077.3
Non-Polymers*	Number of molecules	62
	Total formula weight	14451.5
All*	Total formula weight	240528.8

*Water molecules are not included.