8JQU
Crystal structure of GppNHp bound GTPase domain of Rab5a from Leishmania donovani
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Rab5a | polymer | 175 | 19237.9 | 1 | UniProt (A0A109NYM0) Pfam (PF00071) In PDB | Leishmania donovani | |
2 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
3 | A | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | non-polymer | 522.2 | 1 | Chemie (GNP) | |||
4 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
5 | water | water | 18.0 | 190 | Chemie (HOH) |
Sequence modifications
A: 1 - 175 (UniProt: A0A109NYM0)
PDB | External Database | Details |
---|---|---|
Asp 58 | Pro 58 | engineered mutation |
Gly 59 | Pro 59 | engineered mutation |
- | Pro 60 | deletion |
- | Arg 61 | deletion |
- | Gly 62 | deletion |
- | Ala 63 | deletion |
- | Ala 64 | deletion |
- | Ala 65 | deletion |
- | Ala 66 | deletion |
- | Pro 67 | deletion |
- | Gly 68 | deletion |
- | Gly 69 | deletion |
- | Ala 70 | deletion |
- | Thr 71 | deletion |
- | Ser 72 | deletion |
- | Ala 73 | deletion |
- | His 74 | deletion |
- | Ala 75 | deletion |
- | Leu 76 | deletion |
- | Gln 77 | deletion |
- | Gln 78 | deletion |
- | Met 79 | deletion |
Leu 72 | Gln 92 | engineered mutation |
Ser 87 | Cys 107 | engineered mutation |
- | Leu 196 | deletion |
- | Asp 197 | deletion |
- | Gln 198 | deletion |
- | Gly 199 | deletion |
- | Leu 200 | deletion |
- | Gly 201 | deletion |
- | Asn 202 | deletion |
- | Arg 203 | deletion |
- | Gly 204 | deletion |
- | Gly 205 | deletion |
- | Ala 206 | deletion |
- | Ala 207 | deletion |
- | Gly 208 | deletion |
- | Gly 209 | deletion |
- | Ala 210 | deletion |
- | Arg 211 | deletion |
- | Gly 212 | deletion |
- | Gly 213 | deletion |
- | Val 214 | deletion |
- | Val 215 | deletion |
- | Ala 216 | deletion |
- | Pro 217 | deletion |
- | Arg 218 | deletion |
- | Gly 219 | deletion |
- | Glu 220 | deletion |
- | Arg 221 | deletion |
- | Val 222 | deletion |
- | Glu 223 | deletion |
- | Gln 224 | deletion |
- | Ser 225 | deletion |
- | Asn 226 | deletion |
- | Glu 227 | deletion |
- | Ser 228 | deletion |
- | Ala 229 | deletion |
- | Ser 230 | deletion |
- | Gln 231 | deletion |
- | Ser 232 | deletion |
- | Thr 233 | deletion |
- | Cys 234 | deletion |
- | Cys 235 | deletion |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 19237.9 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 608.6 | |
All* | Total formula weight | 19846.4 |