8JQU
Crystal structure of GppNHp bound GTPase domain of Rab5a from Leishmania donovani
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Rab5a | polymer | 175 | 19237.9 | 1 | UniProt (A0A109NYM0) | Leishmania donovani | |
| 2 | B (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 3 | C (A) | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | non-polymer | 522.2 | 1 | Chemie (GNP) | |||
| 4 | D (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | E (A) | water | water | 18.0 | 190 | Chemie (HOH) |
Sequence modifications
A: 1 - 175 (UniProt: A0A109NYM0)
| PDB | External Database | Details |
|---|---|---|
| Asp 58 | Pro 58 | engineered mutation |
| Gly 59 | Pro 59 | engineered mutation |
| - | Pro 60 | deletion |
| - | Arg 61 | deletion |
| - | Gly 62 | deletion |
| - | Ala 63 | deletion |
| - | Ala 64 | deletion |
| - | Ala 65 | deletion |
| - | Ala 66 | deletion |
| - | Pro 67 | deletion |
| - | Gly 68 | deletion |
| - | Gly 69 | deletion |
| - | Ala 70 | deletion |
| - | Thr 71 | deletion |
| - | Ser 72 | deletion |
| - | Ala 73 | deletion |
| - | His 74 | deletion |
| - | Ala 75 | deletion |
| - | Leu 76 | deletion |
| - | Gln 77 | deletion |
| - | Gln 78 | deletion |
| - | Met 79 | deletion |
| Leu 72 | Gln 92 | engineered mutation |
| Ser 87 | Cys 107 | engineered mutation |
| - | Leu 196 | deletion |
| - | Asp 197 | deletion |
| - | Gln 198 | deletion |
| - | Gly 199 | deletion |
| - | Leu 200 | deletion |
| - | Gly 201 | deletion |
| - | Asn 202 | deletion |
| - | Arg 203 | deletion |
| - | Gly 204 | deletion |
| - | Gly 205 | deletion |
| - | Ala 206 | deletion |
| - | Ala 207 | deletion |
| - | Gly 208 | deletion |
| - | Gly 209 | deletion |
| - | Ala 210 | deletion |
| - | Arg 211 | deletion |
| - | Gly 212 | deletion |
| - | Gly 213 | deletion |
| - | Val 214 | deletion |
| - | Val 215 | deletion |
| - | Ala 216 | deletion |
| - | Pro 217 | deletion |
| - | Arg 218 | deletion |
| - | Gly 219 | deletion |
| - | Glu 220 | deletion |
| - | Arg 221 | deletion |
| - | Val 222 | deletion |
| - | Glu 223 | deletion |
| - | Gln 224 | deletion |
| - | Ser 225 | deletion |
| - | Asn 226 | deletion |
| - | Glu 227 | deletion |
| - | Ser 228 | deletion |
| - | Ala 229 | deletion |
| - | Ser 230 | deletion |
| - | Gln 231 | deletion |
| - | Ser 232 | deletion |
| - | Thr 233 | deletion |
| - | Cys 234 | deletion |
| - | Cys 235 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 19237.9 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 608.6 | |
| All* | Total formula weight | 19846.4 |
