8JLJ
T1AM-bound mTAAR1-Gs protein complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | mGs | polymer | 361 | 41879.5 | 1 | Pfam (PF00503) UniProt (by SIFTS) (P63096) UniProt (by SIFTS) (P63092) In PDB | Homo sapiens | |
| 2 | B | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 358 | 39418.1 | 1 | UniProt (P62873) Pfam (PF00400) In PDB | Homo sapiens (human) | Transducin beta chain 1 |
| 3 | R | Soluble cytochrome b562,Trace amine-associated receptor 1 | polymer | 446 | 50420.7 | 1 | UniProt (P0ABE7) UniProt (Q923Y8) Pfam (PF07361) Pfam (PF00001) In PDB | Escherichia coli | Cytochrome b-562 |
| 4 | S | ScFv16 | polymer | 251 | 26709.7 | 1 | Mus musculus | ||
| 5 | Y | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 71 | 7861.1 | 1 | UniProt (P59768) Pfam (PF00631) In PDB | Homo sapiens (human) | G gamma-I |
| 6 | R | 4-[4-(2-azanylethyl)-2-iodanyl-phenoxy]phenol | non-polymer | 355.2 | 1 | Chemie (UJF) |
Sequence modifications
B: 2 - 340 (UniProt: P62873)
R: -105 - 0 (UniProt: P0ABE7)
R: 1 - 332 (UniProt: Q923Y8)
| PDB | External Database | Details |
|---|---|---|
| Met -17 | - | initiating methionine |
| His -16 | - | expression tag |
| His -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| Leu -10 | - | expression tag |
| Glu -9 | - | expression tag |
| Val -8 | - | expression tag |
| Leu -7 | - | expression tag |
| Phe -6 | - | expression tag |
| Gln -5 | - | expression tag |
| Gly -4 | - | expression tag |
| Pro -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Gly 1 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Asp -113 | - | expression tag |
| Tyr -112 | - | expression tag |
| Lys -111 | - | expression tag |
| Asp -110 | - | expression tag |
| Asp -109 | - | expression tag |
| Asp -108 | - | expression tag |
| Asp -107 | - | expression tag |
| Lys -106 | - | expression tag |
| Trp -99 | Met 29 | engineered mutation |
| Ile -4 | His 124 | engineered mutation |
| Leu 0 | Arg 128 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 166289.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 355.2 | |
| All* | Total formula weight | 166644.3 |
