8JHF
Native SUV420H1 bound to 167-bp nucleosome
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (K) | Histone-lysine N-methyltransferase KMT5B | polymer | 361 | 41330.7 | 1 | UniProt (Q4FZB7) Pfam (PF00856) | Homo sapiens (human) | Lysine N-methyltransferase 5B,Lysine-specific methyltransferase 5B,Suppressor of variegation 4-20 homolog 1,Su(var)4-20 homolog 1,Suv4-20h1,[histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B,[histone H4]-lysine20 N-methyltransferase KMT5B |
| 2 | B, F (A, E) | Histone H3.1 | polymer | 136 | 15437.2 | 2 | UniProt (P68431) Pfam (PF00125) | Homo sapiens (human) | Histone H3/a,Histone H3/b,Histone H3/c,Histone H3/d,Histone H3/f,Histone H3/h,Histone H3/i,Histone H3/j,Histone H3/k,Histone H3/l |
| 3 | C, G (B, F) | Histone H4 | polymer | 86 | 9863.6 | 2 | UniProt (P62805) Pfam (PF15511) | Homo sapiens (human) | |
| 4 | D, H (C, G) | Histone H2A.Z | polymer | 113 | 12219.2 | 2 | UniProt (P0C0S5) Pfam (PF00125) Pfam (PF16211) | Homo sapiens (human) | H2A/z |
| 5 | E, I (D, H) | Histone H2B type 1-K | polymer | 95 | 10607.2 | 2 | UniProt (O60814) Pfam (PF00125) | Homo sapiens (human) | H2B K,HIRA-interacting protein 1 |
| 6 | J (I) | DNA (160-MER) | polymer | 160 | 49038.2 | 1 | Homo sapiens (human) | ||
| 7 | K (J) | DNA (160-MER) | polymer | 160 | 49745.7 | 1 | Homo sapiens (human) | ||
| 8 | L (K) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 9 | M (K) | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 1 | Chemie (SAM) PubChem (5136) PubChem (34755) PubChem (9865603) PubChem (12312798) PubChem (58766358) PubChem (87224684) PubChem (131697735) PubChem (145712080) PubChem (58633578) PubChem (60038769) PubChem (73897310) PubChem (132988922) PubChem (134692588) PubChem (135030730) PubChem (140459785) PubChem (163046094) |
Sequence modifications
B, F: 17 - 102 (UniProt: P62805)
| PDB | External Database | Details |
|---|---|---|
| Met 20 | Lys 21 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 11 |
| Total formula weight | 236368.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 463.8 | |
| All* | Total formula weight | 236832.8 |
