8JHC
FZD3 in inactive state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (R) | Frizzled-3,Soluble cytochrome b562 | polymer | 643 | 74095.1 | 1 | UniProt (Q9NPG1) UniProt (P0ABE7) Pfam (PF01392) Pfam (PF01534) Pfam (PF07361) | Homo sapiens | Fz-3,hFz3 |
| 2 | B (H) | anti-BRIL Fab Heavy chain | polymer | 240 | 25704.6 | 1 | Homo sapiens | ||
| 3 | C (K) | anti-Fab Nanobody | polymer | 134 | 14927.3 | 1 | synthetic construct | ||
| 4 | D (L) | anti-BRIL Fab Light chain | polymer | 212 | 23209.8 | 1 | Homo sapiens |
Sequence modifications
R: 22 - 399 (UniProt: Q9NPG1)
R: 1006 - 1110 (UniProt: P0ABE7)
R: 410 - 514 (UniProt: Q9NPG1)
| PDB | External Database | Details |
|---|---|---|
| Met -18 | - | initiating methionine |
| Lys -17 | - | expression tag |
| Thr -16 | - | expression tag |
| Ile -15 | - | expression tag |
| Ile -14 | - | expression tag |
| Ala -13 | - | expression tag |
| Leu -12 | - | expression tag |
| Ser -11 | - | expression tag |
| Tyr -10 | - | expression tag |
| Ile -9 | - | expression tag |
| Phe -8 | - | expression tag |
| Cys -7 | - | expression tag |
| Leu -6 | - | expression tag |
| Val -5 | - | expression tag |
| Phe -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Asp -2 | - | expression tag |
| Tyr -1 | - | expression tag |
| Lys 0 | - | expression tag |
| Asp 1 | - | expression tag |
| Asp 2 | - | expression tag |
| Asp 3 | - | expression tag |
| Asp 4 | - | expression tag |
| Lys 5 | - | expression tag |
| His 6 | - | expression tag |
| His 7 | - | expression tag |
| His 8 | - | expression tag |
| His 9 | - | expression tag |
| His 10 | - | expression tag |
| His 11 | - | expression tag |
| His 12 | - | expression tag |
| His 13 | - | expression tag |
| His 14 | - | expression tag |
| His 15 | - | expression tag |
| Glu 16 | - | expression tag |
| Asn 17 | - | expression tag |
| Leu 18 | - | expression tag |
| Tyr 19 | - | expression tag |
| Phe 20 | - | expression tag |
| Gln 21 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Arg 999 | - | linker |
| Ile 1000 | - | linker |
| Ala 1001 | - | linker |
| Arg 1002 | - | linker |
| Arg 1003 | - | linker |
| Gln 1004 | - | linker |
| Leu 1005 | - | linker |
| Trp 1012 | Met 29 | conflict |
| Ile 1107 | His 124 | conflict |
| Leu 1111 | - | linker |
| Glu 1112 | - | linker |
| Arg 1113 | - | linker |
| Ala 1114 | - | linker |
| Arg 1115 | - | linker |
| Ser 1116 | - | linker |
| Thr 1117 | - | linker |
| Leu 1118 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 137936.9 | |
| All* | Total formula weight | 137936.9 |
