8JH7
FZD6 in inactive state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | H | anti-BRIL Fab Heavy chain | polymer | 240 | 25704.6 | 1 | Homo sapiens (human) | ||
| 2 | K | anti-Fab Nanobody | polymer | 127 | 14075.4 | 1 | synthetic construct | ||
| 3 | L | anti-BRIL Fab Light chain | polymer | 212 | 23209.8 | 1 | Homo sapiens (human) | ||
| 4 | D | Frizzled-6,Soluble cytochrome b562 | polymer | 641 | 73464.4 | 1 | UniProt (O60353) UniProt (P0ABE7) Pfam (PF01392) Pfam (PF01534) Pfam (PF07361) In PDB | Homo sapiens (human) | Fz-6,hFz6,Cytochrome b-562 |
Sequence modifications
D: 18 - 396 (UniProt: O60353)
D: 1006 - 1110 (UniProt: P0ABE7)
D: 408 - 510 (UniProt: O60353)
| PDB | External Database | Details |
|---|---|---|
| Met -22 | - | initiating methionine |
| Lys -21 | - | expression tag |
| Thr -20 | - | expression tag |
| Ile -19 | - | expression tag |
| Ile -18 | - | expression tag |
| Ala -17 | - | expression tag |
| Leu -16 | - | expression tag |
| Ser -15 | - | expression tag |
| Tyr -14 | - | expression tag |
| Ile -13 | - | expression tag |
| Phe -12 | - | expression tag |
| Cys -11 | - | expression tag |
| Leu -10 | - | expression tag |
| Val -9 | - | expression tag |
| Phe -8 | - | expression tag |
| Ala -7 | - | expression tag |
| Asp -6 | - | expression tag |
| Tyr -5 | - | expression tag |
| Lys -4 | - | expression tag |
| Asp -3 | - | expression tag |
| Asp -2 | - | expression tag |
| Asp -1 | - | expression tag |
| Asp 0 | - | expression tag |
| Lys 1 | - | expression tag |
| His 2 | - | expression tag |
| His 3 | - | expression tag |
| His 4 | - | expression tag |
| His 5 | - | expression tag |
| His 6 | - | expression tag |
| His 7 | - | expression tag |
| His 8 | - | expression tag |
| His 9 | - | expression tag |
| His 10 | - | expression tag |
| His 11 | - | expression tag |
| Glu 12 | - | expression tag |
| Asn 13 | - | expression tag |
| Leu 14 | - | expression tag |
| Tyr 15 | - | expression tag |
| Phe 16 | - | expression tag |
| Gln 17 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Trp 1012 | Met 29 | conflict |
| Ile 1107 | His 124 | conflict |
| Leu 1111 | - | linker |
| Glu 1112 | - | linker |
| Arg 1113 | - | linker |
| Ala 1114 | - | linker |
| Arg 1115 | - | linker |
| Ser 1116 | - | linker |
| Thr 1117 | - | linker |
| Leu 1118 | - | linker |
| Glu | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Ala 1001 | - | linker |
| Arg 1002 | - | linker |
| Arg 1003 | - | linker |
| Gln 1004 | - | linker |
| Leu 1005 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 136454.2 | |
| All* | Total formula weight | 136454.2 |
