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8JH4

RNA polymerase II elongation complex containing 60 bp upstream DNA loop, stalled at SHL(-1) of the nucleosome

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA-directed RNA polymerase subunitpolymer1743194107.41UniProt (C4R4Y0)
Pfam (PF04997)
Pfam (PF05001)
Pfam (PF00623)
Pfam (PF04983)
Pfam (PF05000)
Pfam (PF04998)
Pfam (PF04992)
Pfam (PF04990)
Komagataella phaffii
2B
(B)
DNA-directed RNA polymerase subunit betapolymer1227139746.11UniProt (C4QZQ7)
Pfam (PF04563)
Pfam (PF04561)
Pfam (PF04565)
Pfam (PF04566)
Pfam (PF04567)
Pfam (PF00562)
Pfam (PF04560)
Komagataella phaffii
3C
(C)
RNA polymerase II third largest subunit B44, part of central corepolymer30434216.31UniProt (C4R7L2)
Pfam (PF01193)
Pfam (PF01000)
Komagataella phaffii
4D
(D)
RNA polymerase II subunit B32polymer18620623.01UniProt (C4R2U9)
Pfam (PF03874)
Komagataella phaffii
5E
(E)
DNA-directed RNA polymerases I, II, and III subunit RPABC1polymer21424962.71UniProt (C4R3P8)
Pfam (PF03871)
Pfam (PF01191)
Komagataella phaffii
6F
(F)
RNA polymerase subunit ABC23, common to RNA polymerases I, II, and IIIpolymer15517803.61UniProt (C4R1V1)
Pfam (PF01192)
Komagataella phaffii
7G
(G)
RNA polymerase II subunitpolymer17118802.61UniProt (C4R9A1)
Pfam (PF03876)
Pfam (PF00575)
Komagataella phaffii
8H
(H)
DNA-directed RNA polymerases I, II, and III subunit RPABC3polymer14516249.21UniProt (C4R273)
Pfam (PF03870)
Komagataella phaffii
9I
(I)
DNA-directed RNA polymerase subunitpolymer11513612.31UniProt (F2QPE6)
Pfam (PF02150)
Pfam (PF01096)
Komagataella phaffii
10J
(J)
RNA polymerase subunit ABC10-beta, common to RNA polymerases I, II, and IIIpolymer728554.11UniProt (C4R009)
Pfam (PF01194)
Komagataella phaffii
11K
(K)
RNA polymerase II subunit B12.5polymer11813832.91UniProt (C4R3Z5)
Pfam (PF13656)
Komagataella phaffii
12L
(L)
RNA polymerase subunit ABC10-alphapolymer727862.01UniProt (F2QMI1)
Pfam (PF03604)
Komagataella phaffii
13M
(N)
DNA (198-MER)polymer19861381.91synthetic construct
14N
(P)
RNA (5'-R(P*GP*UP*CP*UP*UP*GP*GP*GP*UP*GP)-3')polymer103210.91synthetic construct
15O
(T)
DNA (198-MER)polymer19860870.01synthetic construct
16P, T
(a, e)
Histone H3.3polymer13615361.02UniProt (P84243)
Pfam (PF00125)
Homo sapiens (human)
17Q, U
(b, f)
Histone H4polymer10311394.42UniProt (P62805)
Pfam (PF15511)
Homo sapiens (human)
18R, V
(c, g)
Histone H2A type 1-B/Epolymer13014165.62UniProt (P04908)
Pfam (PF00125)
Pfam (PF16211)
Homo sapiens (human)
19S, W
(d, h)
Histone H2B type 1-Jpolymer12613935.22UniProt (P06899)
Pfam (PF00125)
Homo sapiens (human)Histone H2B.1,Histone H2B.r,H2B/r
20AA, BA, CA, DA, EA...
(B, C, I, J, L...)
ZINC IONnon-polymer65.48Chemie (ZN)
21Z
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains23
Total formula weight745547.4
Non-Polymers*Number of molecules9
Total formula weight547.6
All*Total formula weight746095.0
*Water molecules are not included.

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PDB entries from 2025-06-18

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