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8JH2

RNA polymerase II elongation complex bound with Elf1, Spt4/5 and foreign DNA, stalled at SHL(-1) of the nucleosome

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(0)
DNA (40-MER)polymer4012306.01synthetic construct
2B
(1)
DNA (40-MER)polymer4012316.81synthetic construct
3C
(A)
DNA-directed RNA polymerase subunitpolymer1743194107.41UniProt (C4R4Y0)
Pfam (PF04997)
Pfam (PF05001)
Pfam (PF00623)
Pfam (PF04983)
Pfam (PF05000)
Pfam (PF04998)
Pfam (PF04992)
Pfam (PF04990)
Komagataella phaffii
4D
(B)
DNA-directed RNA polymerase subunit betapolymer1227139746.11UniProt (C4QZQ7)
Pfam (PF04563)
Pfam (PF04561)
Pfam (PF04565)
Pfam (PF04566)
Pfam (PF04567)
Pfam (PF00562)
Pfam (PF04560)
Komagataella phaffii
5E
(C)
RNA polymerase II third largest subunit B44, part of central corepolymer30434216.31UniProt (C4R7L2)
Pfam (PF01193)
Pfam (PF01000)
Komagataella phaffii
6F
(D)
RNA polymerase II subunit B32polymer18620623.01UniProt (C4R2U9)
Pfam (PF03874)
Komagataella phaffii
7G
(E)
RNA polymerase subunit ABC27polymer21424962.71UniProt (C4R3P8)
Pfam (PF03871)
Pfam (PF01191)
Komagataella phaffiiRNA polymerases I, II, and III
8H
(F)
RNA polymerase subunit ABC23, common to RNA polymerases I, II, and IIIpolymer15517803.61UniProt (C4R1V1)
Pfam (PF01192)
Komagataella phaffii
9I
(G)
RNA polymerase II subunitpolymer17118802.61UniProt (C4R9A1)
Pfam (PF03876)
Pfam (PF00575)
Komagataella phaffii
10J
(H)
DNA-directed RNA polymerases I, II, and III subunit RPABC3polymer14516249.21UniProt (C4R273)
Pfam (PF03870)
Komagataella phaffii
11K
(I)
DNA-directed RNA polymerase subunitpolymer11513612.31UniProt (F2QPE6)
Pfam (PF02150)
Pfam (PF01096)
Komagataella phaffii
12L
(J)
RNA polymerase subunit ABC10-beta, common to RNA polymerases I, II, and IIIpolymer728554.11UniProt (C4R009)
Pfam (PF01194)
Komagataella phaffii
13M
(K)
RNA polymerase II subunit B12.5polymer11813832.91UniProt (C4R3Z5)
Pfam (PF13656)
Komagataella phaffii
14N
(L)
RNA polymerase subunit ABC10-alphapolymer727862.01UniProt (F2QMI1)
Pfam (PF03604)
Komagataella phaffii
15O
(M)
Transcription elongation factor 1 homologpolymer11012395.71UniProt (C4QZ45)
Pfam (PF05129)
Komagataella phaffii
16P
(N)
DNA (218-MER)polymer22870594.71synthetic construct
17Q
(P)
RNA (5'-R(P*CP*CP*UP*GP*GP*UP*GP*UP*CP*UP*UP*GP*GP*GP*UP*G)-3')polymer165124.01synthetic construct
18R
(T)
DNA (218-MER)polymer22870193.91synthetic construct
19S
(V)
Transcription elongation factor SPT4polymer11412627.31UniProt (F2QTA2)
Pfam (PF06093)
UniProt (by SIFTS) (C4R0E6)
Komagataella phaffii
20T
(W)
Transcription elongation factor SPT5polymer908101248.21UniProt (C4R370)
Pfam (PF11942)
Pfam (PF03439)
Pfam (PF00467)
Pfam (PF12815)
Komagataella phaffii
21U, Y
(a, e)
Histone H3.3polymer13615361.02UniProt (P84243)
Pfam (PF00125)
Homo sapiens (human)
22V, Z
(b, f)
Histone H4polymer10311394.42UniProt (P62805)
Pfam (PF15511)
Homo sapiens (human)
23AA, W
(c, g)
Histone H2A type 1-B/Epolymer13014165.62UniProt (P04908)
Pfam (PF00125)
Pfam (PF16211)
Homo sapiens (human)
24BA, X
(d, h)
Histone H2B type 1-Jpolymer12613935.22UniProt (P06899)
Pfam (PF00125)
Homo sapiens (human)Histone H2B.1,Histone H2B.r,H2B/r
25CA, DA, FA, GA, HA...
(A, B, C, I, J...)
ZINC IONnon-polymer65.410Chemie (ZN)
26EA
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains28
Total formula weight916891.3
Non-Polymers*Number of molecules11
Total formula weight678.4
All*Total formula weight917569.7
*Water molecules are not included.

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PDB entries from 2025-06-11

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