8JGA

Cryo-EM structure of Mi3 fused with FKBP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Peptidyl-prolyl cis-trans isomerase FKBP1A,2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase	polymer	344	36730.3	1	UniProt (P62942) UniProt (Q9WXS1) Pfam (PF00254) Pfam (PF01081)	Homo sapiens (human)	PPIase FKBP1A,12 kDa FK506-binding protein,12 kDa FKBP,FKBP-12,Calstabin-1,FK506-binding protein 1A,FKBP-1A,Immunophilin FKBP12,Rotamase

Sequence modifications

A: -118 - -12 (UniProt: P62942)

PDB	External Database	Details
Met -131	-	initiating methionine
Gly -130	-	expression tag
Ser -129	-	expression tag
Ser -128	-	expression tag
His -127	-	expression tag
His -126	-	expression tag
His -125	-	expression tag
His -124	-	expression tag
His -123	-	expression tag
His -122	-	expression tag
Gly -121	-	expression tag
Gly -120	-	expression tag
Ser -119	-	expression tag
Gly -11	-	linker
Gly -10	-	linker
Ser -9	-	linker
Gly -8	-	linker
Gly -7	-	linker
Ser -6	-	linker
Gly -5	-	linker
Gly -4	-	linker
Ser -3	-	linker
Gly -2	-	linker
Gly -1	-	linker
Ser 0	-	linker

A: 1 - 205 (UniProt: Q9WXS1)

PDB	External Database	Details
Lys 26	Glu 26	conflict
Leu 33	Glu 33	conflict
Met 61	Lys 61	conflict
Ala 76	Cys 76	conflict
Ala 100	Cys 100	conflict
Val 187	Asp 187	conflict
Ala 190	Arg 190	conflict
Gly 206	-	expression tag
Ser 207	-	expression tag
Gly 208	-	expression tag
Glu 209	-	expression tag
Pro 210	-	expression tag
Glu 211	-	expression tag
Ala 212	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	36730.3
All*	Total formula weight	36730.3

*Water molecules are not included.