8JF4
The crystal structure of human AURKA kinase domain in complex with AURKA-compound 9
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Aurora kinase A | polymer | 263 | 30566.1 | 1 | UniProt (O14965) Pfam (PF00069) In PDB | Homo sapiens (human) | Aurora 2,Aurora/IPL1-related kinase 1,ARK-1,Aurora-related kinase 1,Breast tumor-amplified kinase,Ipl1- and aurora-related kinase 1,Serine/threonine-protein kinase 15,Serine/threonine-protein kinase 6,Serine/threonine-protein kinase Ayk1,Serine/threonine-protein kinase aurora-A |
| 2 | A | 2-[4-[4-[bis(oxidanylidene)-$l^5-sulfanyl]oxyphenyl]carbonylpiperazin-1-yl]-6-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]-N-prop-2-ynyl-pyrimidine-4-carboxamide | non-polymer | 549.6 | 1 | Chemie (C0N) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 30566.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 549.6 | |
| All* | Total formula weight | 31115.7 |
