8JED
Crystal structure of mRNA cap (guanine-N7) methyltransferase E12 subunit from monkeypox virus and discovery of its inhibitors
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | B | mRNA-capping enzyme regulatory subunit OPG124 | polymer | 296 | 34663.9 | 1 | UniProt (A0A7H0DN96) Pfam (PF03341) In PDB | Monkeypox virus | Virus termination factor small subunit,mRNA-capping enzyme 33 kDa subunit,mRNA-capping enzyme D12 subunit,mRNA-capping enzyme small subunit |
2 | water | water | 18.0 | 178 | Chemie (HOH) |
Sequence modifications
B: 1 - 287 (UniProt: A0A7H0DN96)
PDB | External Database | Details |
---|---|---|
Gly 0 | - | expression tag |
Thr 93 | Ser 93 | conflict |
Thr 242 | Ile 242 | conflict |
His 288 | - | expression tag |
His 289 | - | expression tag |
His 290 | - | expression tag |
His 291 | - | expression tag |
His 292 | - | expression tag |
His 293 | - | expression tag |
His 294 | - | expression tag |
His 295 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 34663.9 | |
All* | Total formula weight | 34663.9 |