8JE6
Crystal Structure of Anopheles culicifacies Prolyl-tRNA Synthetase (AcPRS) in complex with Halofuginone and ATP analogue
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | PROLYL-TRNA SYNTHETASE | polymer | 505 | 58101.0 | 2 | UniProt (A0A182M1F8) | Anopheles culicifacies | |
| 2 | C, G (A, B) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 2 | Chemie (ANP) | |||
| 3 | D, H (A, B) | 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one | non-polymer | 414.7 | 2 | Chemie (HFG) PubChem (37888350) PubChem (37888353) PubChem (46781677) PubChem (70920153) PubChem (60076317) PubChem (62891) PubChem (62894) PubChem (400772) PubChem (456390) | |||
| 4 | E, I (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) PubChem (888) | |||
| 5 | F, J (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) |
Sequence modifications
A, B: 1219 - 1722 (UniProt: A0A182M1F8)
| PDB | External Database | Details |
|---|---|---|
| Met 1218 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 116202.0 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2021.2 | |
| All* | Total formula weight | 118223.2 |
