8JE6
Crystal Structure of Anopheles culicifacies Prolyl-tRNA Synthetase (AcPRS) in complex with Halofuginone and ATP analogue
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | PROLYL-TRNA SYNTHETASE | polymer | 505 | 58101.0 | 2 | UniProt (A0A182M1F8) | Anopheles culicifacies | |
| 2 | C, G (A, B) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 2 | Chemie (ANP) PubChem (4795) PubChem (33113) PubChem (445863) PubChem (6102784) PubChem (9543492) PubChem (14188278) PubChem (16058657) PubChem (23639785) PubChem (24794410) PubChem (44462678) PubChem (46926537) PubChem (54765332) PubChem (60063697) PubChem (66575078) PubChem (89688694) PubChem (92436779) PubChem (93005803) | |||
| 3 | D, H (A, B) | 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one | non-polymer | 414.7 | 2 | Chemie (HFG) PubChem (456390) PubChem (62891) PubChem (62894) PubChem (400772) PubChem (37888350) PubChem (37888353) PubChem (60076317) PubChem (70920153) PubChem (46781677) | |||
| 4 | E, I (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) PubChem (888) | |||
| 5 | F, J (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) |
Sequence modifications
A, B: 1219 - 1722 (UniProt: A0A182M1F8)
| PDB | External Database | Details |
|---|---|---|
| Met 1218 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 116202.0 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2021.2 | |
| All* | Total formula weight | 118223.2 |
