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8JDO

Crystal structure of H405A mLDHD in complex with D-2-hydroxyhexanoic acid

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Probable D-lactate dehydrogenase, mitochondrialpolymer47150385.81UniProt (Q7TNG8)
Pfam (PF01565)
Pfam (PF02913)
Mus musculus (house mouse)DLD,Lactate dehydrogenase D
2B
(A)
(2R)-2-hydroxyhexanoic acidnon-polymer132.21Chemie (7N6)
3C
(A)
FLAVIN-ADENINE DINUCLEOTIDEnon-polymer785.51Chemie (FAD)
4D
(A)
waterwater18.0409Chemie (HOH)
Sequence modifications
A: 22 - 484 (UniProt: Q7TNG8)
PDBExternal DatabaseDetails
Trp 14-expression tag
Ser 15-expression tag
His 16-expression tag
Pro 17-expression tag
Gln 18-expression tag
Phe 19-expression tag
Glu 20-expression tag
Lys 21-expression tag
Ala 405His 405engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight50385.8
Non-Polymers*Number of molecules2
Total formula weight917.7
All*Total formula weight51303.5
*Water molecules are not included.

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PDB entries from 2024-11-06

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