8JDB
Crystal structure of H405A mLDHD in complex with D-2-hydroxyoctanoic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Probable D-lactate dehydrogenase, mitochondrial | polymer | 471 | 50385.8 | 1 | UniProt (Q7TNG8) Pfam (PF01565) Pfam (PF02913) In PDB | Mus musculus (house mouse) | DLD,Lactate dehydrogenase D |
| 2 | A | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 1 | Chemie (FAD) | |||
| 3 | A | (2R)-2-oxidanyloctanoic acid | non-polymer | 160.2 | 1 | Chemie (UIT) | |||
| 4 | water | water | 18.0 | 419 | Chemie (HOH) |
Sequence modifications
A: 22 - 484 (UniProt: Q7TNG8)
| PDB | External Database | Details |
|---|---|---|
| Trp 14 | - | expression tag |
| Ser 15 | - | expression tag |
| His 16 | - | expression tag |
| Pro 17 | - | expression tag |
| Gln 18 | - | expression tag |
| Phe 19 | - | expression tag |
| Glu 20 | - | expression tag |
| Lys 21 | - | expression tag |
| Ala 405 | His 405 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 50385.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 945.8 | |
| All* | Total formula weight | 51331.5 |
