8JB3
Structure and allosteric regulation of the inosine 5'-monophosphate-specific phosphatase ISN1 from Saccharomyces cerevisiae
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | IMP-specific 5'-nucleotidase 1 | polymer | 455 | 52335.2 | 1 | UniProt (Q99312) Pfam (PF06437) | Saccharomyces cerevisiae (baker's yeast) | |
| 2 | B (A) | INOSINE | non-polymer | 268.2 | 1 | Chemie (NOS) | |||
| 3 | C (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 4 | D (A) | INOSINIC ACID | non-polymer | 348.2 | 1 | Chemie (IMP) | |||
| 5 | E, F (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 6 | G (A) | water | water | 18.0 | 189 | Chemie (HOH) |
Sequence modifications
A: 4 - 450 (UniProt: Q99312)
| PDB | External Database | Details |
|---|---|---|
| Ala 172 | Asp 172 | engineered mutation |
| His 451 | - | expression tag |
| His 452 | - | expression tag |
| His 453 | - | expression tag |
| His 454 | - | expression tag |
| His 455 | - | expression tag |
| His 456 | - | expression tag |
| His 457 | - | expression tag |
| His 458 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 52335.2 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 760.0 | |
| All* | Total formula weight | 53095.2 |
