8JA5

Crystal structure of Nipah Virus attachment (G) glycoprotein in complex with neutralizing antibody 14F8

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	H, B	14F8 antibody heavy chain	polymer	233	24968.0	2		Mus musculus
2	L	14F8 antibody light chain	polymer	216	23587.3	1		Mus musculus
3	A, D	Glycoprotein G	polymer	423	47758.2	2	UniProt (Q9IH62) Pfam (PF00423) In PDB	Nipah henipavirus
4	C	14F8 antibody light chain	polymer	219	24081.8	1		Mus musculus
5	E	alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		748.7	1	In PDB GlyTouCan (G81315DD)
6	F	alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1057.0	1	In PDB
7	G, I, K	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	3	In PDB GlyTouCan (G42666HT)
8	J	alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		894.8	1	In PDB GlyTouCan (G00395TQ)
9	A, D	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
10		water	water		18.0	60	Chemie (HOH)

Sequence modifications

A, D: 186 - 602 (UniProt: Q9IH62)

PDB	External Database	Details
His 603	-	expression tag
His 604	-	expression tag
His 605	-	expression tag
His 606	-	expression tag
His 607	-	expression tag
His 608	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	193121.6
Branched	Number of molecules	6
	Total formula weight	3973.7
Non-Polymers*	Number of molecules	2
	Total formula weight	442.4
All*	Total formula weight	197537.6

*Water molecules are not included.