8JA5
Crystal structure of Nipah Virus attachment (G) glycoprotein in complex with neutralizing antibody 14F8
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (H, B) | 14F8 antibody heavy chain | polymer | 233 | 24968.0 | 2 | Mus musculus | ||
| 2 | B (L) | 14F8 antibody light chain | polymer | 216 | 23587.3 | 1 | Mus musculus | ||
| 3 | C, F (A, D) | Glycoprotein G | polymer | 423 | 47758.2 | 2 | UniProt (Q9IH62) Pfam (PF00423) | Nipah henipavirus | |
| 4 | E (C) | 14F8 antibody light chain | polymer | 219 | 24081.8 | 1 | Mus musculus | ||
| 5 | G (E) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G81315DD) | |||
| 6 | H (F) | alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1057.0 | 1 | In PDB | |||
| 7 | I, J, L (G, I, K) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 3 | In PDB GlyTouCan (G42666HT) | |||
| 8 | K (J) | alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 894.8 | 1 | In PDB GlyTouCan (G00395TQ) | |||
| 9 | M, N (A, D) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 10 | O, P, Q, R, S... (H, L, A, B, C...) | water | water | 18.0 | 60 | Chemie (HOH) |
Sequence modifications
A, D: 186 - 602 (UniProt: Q9IH62)
| PDB | External Database | Details |
|---|---|---|
| His 603 | - | expression tag |
| His 604 | - | expression tag |
| His 605 | - | expression tag |
| His 606 | - | expression tag |
| His 607 | - | expression tag |
| His 608 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 193121.6 | |
| Branched | Number of molecules | 6 |
| Total formula weight | 3973.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 442.4 | |
| All* | Total formula weight | 197537.6 |
