8J9O
Cryo-EM structure of inactive FZD1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Frizzled-1,Soluble cytochrome b562 | polymer | 677 | 75034.2 | 1 | UniProt (Q9UP38) UniProt (P0ABE7) Pfam (PF01392) Pfam (PF01534) Pfam (PF07361) | Homo sapiens (human) | Fz-1,hFz1,FzE1 |
| 2 | B (B) | anti-BRIL Fab Heavy Chain | polymer | 263 | 28035.4 | 1 | Mus | ||
| 3 | C (C) | anti-Fab nanobody | polymer | 123 | 13390.6 | 1 | Vicugna pacos | ||
| 4 | D (D) | anti-BRIL Fab Light Chain | polymer | 224 | 24557.4 | 1 | Mus |
Sequence modifications
A: 69 - 514 (UniProt: Q9UP38)
A: 1006 - 1110 (UniProt: P0ABE7)
A: 528 - 637 (UniProt: Q9UP38)
A: 1006 - 1110 (UniProt: P0ABE7)
| PDB | External Database | Details |
|---|---|---|
| Trp 1012 | Met 29 | conflict |
| Ile 1107 | His 124 | conflict |
| Leu 1111 | - | linker |
| Glu 1112 | - | linker |
| Arg 1113 | - | linker |
| Ala 1114 | - | linker |
| Arg 1115 | - | linker |
| Ser 1116 | - | linker |
| Thr 1117 | - | linker |
| Leu 1118 | - | linker |
| Lys | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Ile 999 | - | linker |
| Arg 1000 | - | linker |
| Ala 1001 | - | linker |
| Arg 1002 | - | linker |
| Arg 1003 | - | linker |
| Gln 1004 | - | linker |
| Leu 1005 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 141017.6 | |
| All* | Total formula weight | 141017.6 |
