8J7Q
The active site mutant of human inorganic pyrophosphatase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Inorganic pyrophosphatase | polymer | 289 | 32547.0 | 1 | UniProt (Q15181) Pfam (PF00719) | Homo sapiens (human) | Pyrophosphate phospho-hydrolase,PPase |
| 2 | B (A) | water | water | 18.0 | 196 | Chemie (HOH) |
Sequence modifications
A: 1 - 289 (UniProt: Q15181)
| PDB | External Database | Details |
|---|---|---|
| Ala 116 | Asp 116 | engineered mutation |
| Ala 118 | Asp 118 | engineered mutation |
| Ala 119 | Pro 119 | engineered mutation |
| Ala 121 | Asp 121 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32547.0 | |
| All* | Total formula weight | 32547.0 |
