8J71
Selenomethionine mutant (L601Sem/L654Sem) of SAND domain of protein SP140 with DNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Nuclear body protein SP140 | polymer | 99 | 11498.1 | 2 | UniProt (Q13342) Pfam (PF01342) | Homo sapiens (human) | Lymphoid-restricted homolog of Sp100,LYSp100,Nuclear autoantigen Sp-140,Speckled 140 kDa |
| 2 | C, D (C, D) | DNA (5'-D(*GP*GP*GP*CP*GP*GP*CP*CP*GP*CP*CP*CP*T)-3') | polymer | 13 | 3969.6 | 2 | Homo sapiens | ||
| 3 | E, F, G, H (A, B, C, D) | water | water | 18.0 | 262 | Chemie (HOH) |
Sequence modifications
A, B: 580 - 673 (UniProt: Q13342)
| PDB | External Database | Details |
|---|---|---|
| Gly 575 | - | expression tag |
| Pro 576 | - | expression tag |
| Leu 577 | - | expression tag |
| Gly 578 | - | expression tag |
| Ser 579 | - | expression tag |
| Mse 601 | Leu 601 | engineered mutation |
| Mse 654 | Leu 654 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 30935.3 | |
| All* | Total formula weight | 30935.3 |
