8J71
Selenomethionine mutant (L601Sem/L654Sem) of SAND domain of protein SP140 with DNA
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Nuclear body protein SP140 | polymer | 99 | 11498.1 | 2 | UniProt (Q13342) Pfam (PF01342) In PDB | Homo sapiens (human) | Lymphoid-restricted homolog of Sp100,LYSp100,Nuclear autoantigen Sp-140,Speckled 140 kDa |
2 | C, D | DNA (5'-D(*GP*GP*GP*CP*GP*GP*CP*CP*GP*CP*CP*CP*T)-3') | polymer | 13 | 3969.6 | 2 | Homo sapiens | ||
3 | water | water | 18.0 | 262 | Chemie (HOH) |
Sequence modifications
A, B: 580 - 673 (UniProt: Q13342)
PDB | External Database | Details |
---|---|---|
Gly 575 | - | expression tag |
Pro 576 | - | expression tag |
Leu 577 | - | expression tag |
Gly 578 | - | expression tag |
Ser 579 | - | expression tag |
Mse 601 | Leu 601 | engineered mutation |
Mse 654 | Leu 654 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 30935.3 | |
All* | Total formula weight | 30935.3 |