8J0K

Crystal structure of human TFAP2A in complex with DNA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Transcription factor AP-2-alpha	polymer	219	23819.3	2	UniProt (P05549) Pfam (PF03299)	Homo sapiens (human)	AP2-alpha,AP-2 transcription factor,Activating enhancer-binding protein 2-alpha,Activator protein 2,AP-2
2	C (C)	DNA (5'-D(*CP*TP*GP*CP*CP*TP*CP*GP*GP*GP*CP*AP*C)-3')	polymer	13	3928.5	1		synthetic construct
3	D (D)	DNA (5'-D(*GP*TP*GP*CP*CP*CP*GP*AP*GP*GP*CP*AP*G)-3')	polymer	13	4017.6	1		synthetic construct
4	E, F, I, J, L... (A, B)	TRIETHYLENE GLYCOL	non-polymer		150.2	6	Chemie (PGE)
5	G, N (A, B)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
6	H, K (A, B)	GUANIDINE-3-PROPANOL	non-polymer		118.2	2	Chemie (PG3)
7	O, P, Q, R (A, B, C, D)	water	water		18.0	303	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	55584.8
Non-Polymers*	Number of molecules	10
	Total formula weight	1321.5
All*	Total formula weight	56906.4

*Water molecules are not included.