8J02
Human KCNQ2(F104A)-CaM-PIP2-CBD complex in state II
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, D, G | Potassium voltage-gated channel subfamily KQT member 2 | polymer | 656 | 73551.7 | 4 | UniProt (O43526) Pfam (PF00520) Pfam (PF03520) Pfam (PF16642) In PDB | Homo sapiens (human) | KQT-like 2,Neuroblastoma-specific potassium channel subunit alpha KvLQT2,Voltage-gated potassium channel subunit Kv7.2 |
2 | C, E, H, F | Calmodulin-1 | polymer | 177 | 19615.4 | 4 | UniProt (P0DP23) Pfam (PF13499) In PDB | Homo sapiens (human) | |
3 | A, B, D, G | cannabidiol | non-polymer | 314.5 | 4 | Chemie (P0T) | |||
4 | A, B, D, G | [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate | non-polymer | 746.6 | 4 | Chemie (PIO) |
Sequence modifications
A, B, D, G: 64 - 703 (UniProt: O43526)
C, E, H, F: 1 - 149 (UniProt: P0DP23)
PDB | External Database | Details |
---|---|---|
Met 63 | - | initiating methionine |
Ala 104 | Phe 104 | conflict |
Val 703 | Ala 703 | conflict |
Glu 704 | - | expression tag |
Gly 705 | - | expression tag |
Gly 706 | - | expression tag |
Ser 707 | - | expression tag |
Ser 708 | - | expression tag |
Gly 709 | - | expression tag |
Gly 710 | - | expression tag |
Trp 711 | - | expression tag |
Ser 712 | - | expression tag |
His 713 | - | expression tag |
Pro 714 | - | expression tag |
Gln 715 | - | expression tag |
Phe 716 | - | expression tag |
Glu 717 | - | expression tag |
Lys 718 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Leu 150 | - | expression tag |
Glu 151 | - | expression tag |
Gly 152 | - | expression tag |
Gly 153 | - | expression tag |
Ser 154 | - | expression tag |
Ser 155 | - | expression tag |
Gly 156 | - | expression tag |
Gly 157 | - | expression tag |
Leu 158 | - | expression tag |
Val 159 | - | expression tag |
Pro 160 | - | expression tag |
Arg 161 | - | expression tag |
Gly 162 | - | expression tag |
Ser 163 | - | expression tag |
Gly 164 | - | expression tag |
Gly 165 | - | expression tag |
Ser 166 | - | expression tag |
Ser 167 | - | expression tag |
Gly 168 | - | expression tag |
Gly 169 | - | expression tag |
His 170 | - | expression tag |
His 171 | - | expression tag |
His 172 | - | expression tag |
His 173 | - | expression tag |
His 174 | - | expression tag |
His 175 | - | expression tag |
His 176 | - | expression tag |
His 177 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 372668.7 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 4244.1 | |
All* | Total formula weight | 376912.8 |