8IYA
Complex of SETDB1-derived peptide bound to UBE2E1
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | B, A, C | Ubiquitin-conjugating enzyme E2 E1 | polymer | 170 | 19203.8 | 3 | UniProt (P51965) Pfam (PF00179) In PDB | Homo sapiens (human) | (E3-independent) E2 ubiquitin-conjugating enzyme E1,E2 ubiquitin-conjugating enzyme E1,UbcH6,Ubiquitin carrier protein E1,Ubiquitin-protein ligase E1 |
2 | D, E, F | Histone-lysine N-methyltransferase SETDB1 | polymer | 6 | 686.7 | 3 | UniProt (Q15047) In PDB | Homo sapiens (human) | ERG-associated protein with SET domain,ESET,Histone H3-K9 methyltransferase 4,H3-K9-HMTase 4,Lysine N-methyltransferase 1E,SET domain bifurcated 1 |
3 | B, A, C | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
4 | water | water | 18.0 | 36 | Chemie (HOH) |
Sequence modifications
B, A, C: 41 - 193 (UniProt: P51965)
D, E, F: 1 - 6 (UniProt: Q15047)
PDB | External Database | Details |
---|---|---|
Met 24 | - | initiating methionine |
His 25 | - | expression tag |
His 26 | - | expression tag |
His 27 | - | expression tag |
His 28 | - | expression tag |
His 29 | - | expression tag |
His 30 | - | expression tag |
His 31 | - | expression tag |
His 32 | - | expression tag |
Leu 33 | - | expression tag |
Glu 34 | - | expression tag |
Val 35 | - | expression tag |
Leu 36 | - | expression tag |
Phe 37 | - | expression tag |
Gln 38 | - | expression tag |
Gly 39 | - | expression tag |
Pro 40 | - | expression tag |
Ser 67 | Cys 67 | engineered mutation |
Pro 122 | Cys 122 | engineered mutation |
Ser 153 | Cys 153 | engineered mutation |
Pro 159 | Cys 159 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Cys 1 | Lys 867 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 59671.6 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 288.2 | |
All* | Total formula weight | 59959.8 |