8IXA

GMPCPP-Alpha1A/Beta2A-microtubule decorated with kinesin non-seam region

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D, G, J, M... (I, A, B, C, D...)	Tubulin alpha-1A chain	polymer	457	51017.3	9	UniProt (P68369) Pfam (PF00091) Pfam (PF03953)	Mus musculus (house mouse)	Alpha-tubulin 1,Alpha-tubulin isotype M-alpha-1,Tubulin alpha-1 chain
2	B, E, H, K, N... (Q, J, K, L, M...)	Tubulin beta-2A chain	polymer	457	51151.0	9	UniProt (Q7TMM9) Pfam (PF00091) Pfam (PF03953)	Mus musculus (house mouse)
3	AA, C, F, I, L... (Y, S, T, U, V...)	Kinesin-1 heavy chain	polymer	372	41721.1	9	UniProt (P33176) Pfam (PF00225)	Homo sapiens (human)	Conventional kinesin heavy chain,Ubiquitous kinesin heavy chain,UKHC
4	BA, EA, HA, KA, NA... (Q, J, K, L, M...)	GUANOSINE-5'-TRIPHOSPHATE	non-polymer		523.2	9	Chemie (GTP)
5	AB, CA, FA, IA, LA... (R, Q, J, K, L...)	PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER	non-polymer		521.2	9	Chemie (G2P)
6	BB, DA, GA, JA, MA... (a, Y, S, T, U...)	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	9	Chemie (ATP)

Sequence modifications

I, A, B, C, D, E, F, G, H: 1 - 457 (UniProt: P68369)

PDB	External Database	Details
His 43	-	insertion
His 44	-	insertion
His 45	-	insertion
His 46	-	insertion
His 47	-	insertion
His 48	-	insertion

Q, J, K, L, M, N, O, P, R: 1 - 445 (UniProt: Q7TMM9)

PDB	External Database	Details
Gly 446	-	expression tag
Gly 447	-	expression tag
Ser 448	-	expression tag
Gly 449	-	expression tag
Gly 450	-	expression tag
Asp 451	-	expression tag
Tyr 452	-	expression tag
Lys 453	-	expression tag
Asp 454	-	expression tag
Asp 455	-	expression tag
Asp 456	-	expression tag
Lys 457	-	expression tag

Y, S, T, U, V, W, X, Z, a: 1 - 349 (UniProt: P33176)

PDB	External Database	Details
Met -22	-	initiating methionine
Gly -21	-	expression tag
Ser -20	-	expression tag
Ser -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
Ser -12	-	expression tag
Ser -11	-	expression tag
Gly -10	-	expression tag
Leu -9	-	expression tag
Val -8	-	expression tag
Pro -7	-	expression tag
Arg -6	-	expression tag
Gly -5	-	expression tag
Ser -4	-	expression tag
His -3	-	expression tag
Met -2	-	expression tag
Ala -1	-	expression tag
Ser 0	-	expression tag
Ala 236	Glu 236	conflict

Contents of the asymmetric unit

Polymers	Number of chains	27
	Total formula weight	1295004.1
Non-Polymers*	Number of molecules	27
	Total formula weight	13964.1
All*	Total formula weight	1308968.2

*Water molecules are not included.