8IVX
Crystal structure of NRP2 in complex with aNRP2-14 Fab fragment
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | aNRP2-14 | polymer | 583 | 65954.9 | 1 | UniProt (O60462) Pfam (PF00431) Pfam (PF00754) | Homo sapiens (human) | Vascular endothelial cell growth factor 165 receptor 2 |
| 2 | B (H) | Heavy chain of antibody 14V4 Fab fragment | polymer | 231 | 24742.5 | 1 | Homo sapiens | ||
| 3 | C (L) | Light chain of antibody 14V4 Fab fragment | polymer | 215 | 23785.2 | 1 | Homo sapiens | ||
| 4 | D (H) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 5 | E, F, G (A, H, L) | water | water | 18.0 | 416 | Chemie (HOH) |
Sequence modifications
A: 25 - 595 (UniProt: O60462)
| PDB | External Database | Details |
|---|---|---|
| His 13 | - | expression tag |
| His 14 | - | expression tag |
| His 15 | - | expression tag |
| His 16 | - | expression tag |
| His 17 | - | expression tag |
| His 18 | - | expression tag |
| Glu 19 | - | expression tag |
| Asn 20 | - | expression tag |
| Leu 21 | - | expression tag |
| Tyr 22 | - | expression tag |
| Phe 23 | - | expression tag |
| Gln 24 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 114482.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 62.1 | |
| All* | Total formula weight | 114544.7 |
