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8IV5

Cryo-EM structure of SARS-CoV-2 spike protein in complex with double nAbs 8H12 and 1C4 (local refinement)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(G)
Spike protein S1polymer20422930.71UniProt (P0DTC2)
Pfam (PF09408)
Severe acute respiratory syndrome coronavirus 2
2B
(L)
light chain of 8H12polymer10711945.61Mus musculus
3C
(H)
heavy chain of 8H12polymer11913240.81Mus musculus
4D
(B)
light chain of 1C4polymer10711642.91Mus musculus
5E
(A)
heavy chain of 1C4polymer11913384.91Mus musculus
6F
(C)
beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched586.51In PDB
GlyTouCan (G15407YE)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight73144.8
BranchedNumber of molecules1
Total formula weight586.5
All*Total formula weight73731.4
*Water molecules are not included.

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PDB entries from 2025-06-11

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