8ISR
Crystal structure of extended-spectrum class A beta-lactamase, CESS-1 E166Q acylated by cefaclor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Beta-lactamase | polymer | 269 | 28652.3 | 2 | UniProt (A0A126NGE0) Pfam (PF00144) Pfam (PF13354) In PDB | Stenotrophomonas sp. KCTC 12332 | CESS-1 |
2 | A, B | (R)-2-((R)-((R)-2-amino-2-phenylacetamido)(carboxy)methyl)-5-chloro-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid | non-polymer | 385.8 | 2 | Chemie (Q6R) | |||
3 | A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
4 | water | water | 18.0 | 501 | Chemie (HOH) |
Sequence modifications
A, B: 26 - 291 (UniProt: A0A126NGE0)
PDB | External Database | Details |
---|---|---|
Gly 22 | - | cloning artifact |
Ser 23 | - | cloning artifact |
His 24 | - | cloning artifact |
Met 25 | - | cloning artifact |
Gln 166 | Glu 173 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 57304.6 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 1019.9 | |
All* | Total formula weight | 58324.5 |