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8IPX

human nuclear pre-60S ribosomal particle - State C'

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(2)
28S rRNApolymer50541636424.51Homo sapiens (human)
2B
(6)
Eukaryotic translation initiation factor 6polymer24526620.01UniProt (P56537)
Pfam (PF01912)
Homo sapiens (human)eIF-6,B(2)GCN homolog,B4 integrin interactor,CAB,p27(BBP)
3C
(7)
Probable ribosome biogenesis protein RLP24polymer16319666.31UniProt (Q9UHA3)
Pfam (PF01246)
Homo sapiens (human)Ribosomal L24 domain-containing protein 1,Ribosomal protein L24-like
4D
(8)
5.8S rRNApolymer15650157.71GenBank (KY962518)Homo sapiens (human)
5E
(9)
Zinc finger protein 593polymer13415230.21UniProt (O00488)
Pfam (PF12171)
Homo sapiens (human)Zinc finger protein T86
6F
(A)
60S ribosomal protein L29polymer15917804.31UniProt (P47914)
Pfam (PF01779)
Homo sapiens (human)Large ribosomal subunit protein eL29
7G
(B)
60S ribosomal protein L3polymer40346211.11UniProt (P39023)
Pfam (PF00297)
Homo sapiens (human)Large ribosomal subunit protein uL3
8H
(D)
60S ribosomal protein L4polymer42747804.61UniProt (P36578)
Pfam (PF00573)
Pfam (PF14374)
Homo sapiens (human)Large ribosomal subunit protein uL4
9I
(E)
60S ribosomal protein L30polymer11512805.11UniProt (P62888)
Pfam (PF01248)
Homo sapiens (human)Large ribosomal subunit protein eL30
10J
(G)
60S ribosomal protein L7apolymer26630061.81UniProt (P62424)
Pfam (PF01248)
Homo sapiens (human)Large ribosomal subunit protein eL8
11K
(H)
60S ribosomal protein L35polymer12314593.61UniProt (P42766)
Pfam (PF00831)
Homo sapiens (human)Large ribosomal subunit protein uL29
12L
(I)
60S ribosomal protein L9polymer19221899.51UniProt (P32969)
Pfam (PF00347)
Homo sapiens (human)Large ribosomal subunit protein uL6
13M
(J)
Ribosome biogenesis protein NSA2 homologpolymer26030136.71UniProt (O95478)
Pfam (PF01201)
Homo sapiens (human)Hairy cell leukemia protein 1,TGF-beta-inducible nuclear protein 1
14N
(L)
60S ribosomal protein L27apolymer14816604.51UniProt (P46776)
Pfam (PF00828)
Homo sapiens (human)Large ribosomal subunit protein uL15
15O
(M)
60S ribosomal protein L37polymer9711111.01UniProt (P61927)
Pfam (PF01907)
Homo sapiens (human)Large ribosomal subunit protein eL37
16P
(P)
60S ribosomal protein L39polymer516426.81UniProt (P62891)
Pfam (PF00832)
Homo sapiens (human)Large ribosomal subunit protein eL39
17Q
(Q)
60S ribosomal protein L13polymer21124321.71UniProt (P26373)
Pfam (PF01294)
Homo sapiens (human)Large ribosomal subunit protein eL13
18R
(S)
60S ribosomal protein L14polymer21523485.01UniProt (P50914)
Pfam (PF01929)
Homo sapiens (human)Large ribosomal subunit protein eL14
19S
(U)
60S ribosomal protein L15polymer20424207.31UniProt (P61313)
Pfam (PF00827)
Homo sapiens (human)Large ribosomal subunit protein eL15
20T
(V)
60S ribosomal protein L13apolymer20323633.41UniProt (P40429)
Pfam (PF00572)
Homo sapiens (human)Large ribosomal subunit protein uL13
21U
(X)
60S ribosomal protein L37apolymer9210299.41UniProt (P61513)
Pfam (PF01780)
Homo sapiens (human)Large ribosomal subunit protein eL43
22V
(Z)
60S ribosomal protein L18polymer18821687.71UniProt (Q07020)
Pfam (PF17135)
Homo sapiens (human)Large ribosomal subunit protein eL18
23W
(a)
60S ribosomal protein L19polymer19623535.31UniProt (P84098)
Pfam (PF01280)
Homo sapiens (human)Large ribosomal subunit protein eL19
24X
(b)
60S ribosomal protein L18apolymer17620808.51UniProt (Q02543)
Pfam (PF01775)
Homo sapiens (human)Large ribosomal subunit protein eL20
25Y
(e)
60S ribosomal protein L23polymer14014892.51UniProt (P62829)
Pfam (PF00238)
Homo sapiens (human)Large ribosomal subunit protein uL14
26Z
(h)
60S ribosomal protein L26polymer14517303.41UniProt (P61254)
Pfam (PF16906)
Pfam (PF00467)
Homo sapiens (human)Large ribosomal subunit protein uL24
27AA
(l)
60S ribosomal protein L28polymer13715784.61UniProt (P46779)
Pfam (PF01778)
Homo sapiens (human)Large ribosomal subunit protein eL28
28BA
(m)
60S ribosomal protein L8polymer25728088.91UniProt (P62917)
Pfam (PF00181)
Pfam (PF03947)
Homo sapiens (human)Large ribosomal subunit protein uL2
29CA
(n)
60S ribosomal protein L35apolymer11012564.71UniProt (P18077)
Pfam (PF01247)
Homo sapiens (human)Large ribosomal subunit protein eL33
30DA
(o)
60S ribosomal protein L6polymer28832810.21UniProt (Q02878)
Pfam (PF03868)
Pfam (PF01159)
Homo sapiens (human)Large ribosomal subunit protein eL6
31EA
(p)
60S ribosomal protein L7polymer24829291.01UniProt (P18124)
Pfam (PF08079)
Pfam (PF00327)
Homo sapiens (human)Large ribosomal subunit protein uL30
32FA
(r)
Coiled-coil domain-containing protein 86polymer36040312.71UniProt (Q9H6F5)
Pfam (PF03879)
Homo sapiens (human)Cytokine-induced protein with coiled-coil domain
33GA
(u)
Guanine nucleotide-binding protein-like 3polymer54962098.21UniProt (Q9BVP2)
Pfam (PF08701)
Pfam (PF01926)
Homo sapiens (human)E2-induced gene 3 protein,Novel nucleolar protein 47,NNP47,Nucleolar GTP-binding protein 3,Nucleostemin
34HA
(v)
mRNA turnover protein 4 homologpolymer23927602.51UniProt (Q9UKD2)
Pfam (PF00466)
Pfam (PF17777)
Homo sapiens (human)Ribosome assembly factor MRTO4
35IA
(w)
G Protein Nucleolar 2polymer73183796.11UniProt (Q13823)
Pfam (PF08153)
Pfam (PF01926)
Homo sapiens (human)Autoantigen NGP-1
36JA
(y)
60S ribosomal protein L12polymer16517847.61UniProt (P30050)
Pfam (PF03946)
Pfam (PF00298)
Homo sapiens (human)Large ribosomal subunit protein uL11
37KA
(z)
Protein LLP homologpolymer12915268.41UniProt (Q9BRT6)
Pfam (PF10169)
Homo sapiens (human)Protein LAPS18-like
38LA
(C)
60S ribosomal protein L11polymer17820288.51UniProt (P62913)
Pfam (PF00281)
Pfam (PF00673)
Homo sapiens (human)Large ribosomal subunit protein uL5
39MA
(R)
60S ribosomal protein L5polymer29734426.81UniProt (P46777)
Pfam (PF17144)
Pfam (PF14204)
Homo sapiens (human)Large ribosomal subunit protein uL18
40NA
(W)
Notchless protein homolog 1polymer48553387.11UniProt (Q9NVX2)
Pfam (PF08154)
Pfam (PF00400)
Homo sapiens (human)
41OA
(T)
60S ribosomal protein L21polymer16018610.01UniProt (P46778)
Pfam (PF01157)
Homo sapiens (human)Large ribosomal subunit protein eL21
42PA
(4)
GTP-binding protein 4polymer63474107.81UniProt (Q9BZE4)
Pfam (PF17835)
Pfam (PF06858)
Pfam (PF08155)
Homo sapiens (human)Chronic renal failure gene protein,GTP-binding protein NGB
43QA
(Y)
60S ribosomal protein L17polymer18421443.21UniProt (P18621)
Pfam (PF00237)
Homo sapiens (human)Large ribosomal subunit protein uL22
44RA
(k)
60S ribosomal protein L32polymer13515898.91UniProt (P62910)
Pfam (PF01655)
Homo sapiens (human)Large ribosomal subunit protein eL32
45SA
(j)
60S ribosomal protein L31polymer12514494.91UniProt (P62899)
Pfam (PF01198)
Homo sapiens (human)Large ribosomal subunit protein eL31
46TA
(d)
60S ribosomal protein L22polymer12814813.01UniProt (P35268)
Pfam (PF01776)
Homo sapiens (human)Large ribosomal subunit protein eL22
47UA
(t)
MKI67 FHA domain-interacting nucleolar phosphoproteinpolymer29334285.31UniProt (Q9BYG3)
Pfam (PF00076)
Pfam (PF12196)
Homo sapiens (human)Nucleolar phosphoprotein Nopp34,Nucleolar protein interacting with the FHA domain of pKI-67,hNIFK
48VA
(x)
ITS2polymer6011720.71Homo sapiens (human)
49WA
(N)
Ribosomal L1 domain-containing protein 1polymer49055089.81UniProt (O76021)
Pfam (PF00687)
Homo sapiens (human)CATX-11,Cellular senescence-inhibited gene protein,Protein PBK1
50XA
(1)
60S ribosomal protein L7-like 1polymer25529730.41UniProt (Q6DKI1)
Pfam (PF08079)
Pfam (PF00327)
Homo sapiens (human)Large ribosomal subunit protein uL30-like 1
51YA
(K)
60S ribosomal protein L36polymer10512290.91UniProt (Q9Y3U8)
Pfam (PF01158)
Homo sapiens (human)Large ribosomal subunit protein eL36
52ZA
(F)
60S ribosomal protein L34polymer11713326.11UniProt (P49207)
Pfam (PF01199)
Homo sapiens (human)Large ribosomal subunit protein eL34
53AB
(i)
60S ribosomal protein L27polymer13615835.81UniProt (P61353)
Pfam (PF00467)
Pfam (PF01777)
Homo sapiens (human)Large ribosomal subunit protein eL27
54BB
(O)
60S ribosomal protein L38polymer708238.91UniProt (P63173)
Pfam (PF01781)
Homo sapiens (human)Large ribosomal subunit protein eL38
55CB
(3)
5S RNApolymer12038651.91GenBank (NR_023363)Homo sapiens (human)
56DB
(q)
Pescadillo homologpolymer58868114.71UniProt (O00541)
Pfam (PF06732)
Pfam (PF16589)
Homo sapiens (human)
57EB
(g)
60S ribosomal protein L23apolymer15617740.21UniProt (P62750)
Pfam (PF03939)
Pfam (PF00276)
Homo sapiens (human)Large ribosomal subunit protein uL23
58FB
(f)
Ribosome biogenesis protein NOP53polymer47854498.41UniProt (Q9NZM5)
Pfam (PF07767)
Homo sapiens (human)Glioma tumor suppressor candidate region gene 2 protein,Protein interacting with carboxyl terminus 1,PICT-1,p60
59GB
(w)
GUANOSINE-5'-TRIPHOSPHATEnon-polymer523.21Chemie (GTP)
60HB
(w)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
Sequence modifications
3: 1 - 120 (GenBank: NR_023363)
PDBExternal DatabaseDetails
C 92G 93conflict
G 93C 94conflict
C 95U 96conflict
U 96G 97conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains58
Total formula weight3200190.1
Non-Polymers*Number of molecules2
Total formula weight547.5
All*Total formula weight3200737.5
*Water molecules are not included.

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PDB entries from 2024-10-30

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