8IO0

Cryo-EM structure of human HCN3 channel with cAMP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3	polymer	774	86142.9	4	UniProt (Q9P1Z3) Pfam (PF08412) Pfam (PF00520) Pfam (PF00027)	Homo sapiens (human)
2	E, F, G, H (A, B, C, D)	ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE	non-polymer		329.2	4	Chemie (CMP)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	344571.7
Non-Polymers*	Number of molecules	4
	Total formula weight	1316.8
All*	Total formula weight	345888.5

*Water molecules are not included.