8INE

human nuclear pre-60S ribosomal particle - State G'

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (u)	Ribosomal L1 domain-containing protein 1	polymer	490	55089.8	1	UniProt (O76021) Pfam (PF00687)	Homo sapiens (human)	CATX-11,Cellular senescence-inhibited gene protein,Protein PBK1
2	B (t)	MKI67 FHA domain-interacting nucleolar phosphoprotein	polymer	293	34285.3	1	UniProt (Q9BYG3) Pfam (PF00076) Pfam (PF12196)	Homo sapiens (human)	Nucleolar phosphoprotein Nopp34,Nucleolar protein interacting with the FHA domain of pKI-67,hNIFK
3	C (3)	60S ribosomal protein L7-like 1	polymer	255	29730.4	1	UniProt (Q6DKI1) Pfam (PF08079) Pfam (PF00327)	Homo sapiens (human)	Large ribosomal subunit protein uL30-like 1
4	D (2)	28S rRNA	polymer	5054	1636653.0	1		Homo sapiens (human)
5	E (4)	GTP-binding protein 4	polymer	634	74107.8	1	UniProt (Q9BZE4) Pfam (PF17835) Pfam (PF06858) Pfam (PF08155)	Homo sapiens (human)	Chronic renal failure gene protein,GTP-binding protein NGB
6	F (5)	5S rRNA	polymer	120	38691.9	1	GenBank (NR_023363)	Homo sapiens (human)
7	G (6)	Eukaryotic translation initiation factor 6	polymer	245	26620.0	1	UniProt (P56537) Pfam (PF01912)	Homo sapiens (human)	eIF-6,B(2)GCN homolog,B4 integrin interactor,CAB,p27(BBP)
8	H (7)	Probable ribosome biogenesis protein RLP24	polymer	163	19666.3	1	UniProt (Q9UHA3) Pfam (PF01246)	Homo sapiens (human)	Ribosomal L24 domain-containing protein 1,Ribosomal protein L24-like
9	I (9)	Zinc finger protein 593	polymer	134	15230.2	1	UniProt (O00488) Pfam (PF12171)	Homo sapiens (human)	Zinc finger protein T86
10	J (B)	60S ribosomal protein L3	polymer	403	46211.1	1	UniProt (P39023) Pfam (PF00297)	Homo sapiens (human)	Large ribosomal subunit protein uL3
11	K (C)	60S ribosomal protein L29	polymer	159	17804.3	1	UniProt (P47914) Pfam (PF01779)	Homo sapiens (human)	Large ribosomal subunit protein eL29
12	L (D)	60S ribosomal protein L4	polymer	427	47804.6	1	UniProt (P36578) Pfam (PF00573) Pfam (PF14374)	Homo sapiens (human)	Large ribosomal subunit protein uL4
13	M (E)	60S ribosomal protein L30	polymer	115	12805.1	1	UniProt (P62888) Pfam (PF01248)	Homo sapiens (human)	Large ribosomal subunit protein eL30
14	N (F)	60S ribosomal protein L34	polymer	117	13326.1	1	UniProt (P49207) Pfam (PF01199)	Homo sapiens (human)	Large ribosomal subunit protein eL34
15	O (G)	60S ribosomal protein L7a	polymer	266	30061.8	1	UniProt (P62424) Pfam (PF01248)	Homo sapiens (human)	Large ribosomal subunit protein eL8
16	P (H)	60S ribosomal protein L35	polymer	123	14593.6	1	UniProt (P42766) Pfam (PF00831)	Homo sapiens (human)	Large ribosomal subunit protein uL29
17	Q (I)	60S ribosomal protein L9	polymer	192	21899.5	1	UniProt (P32969) Pfam (PF00347)	Homo sapiens (human)	Large ribosomal subunit protein uL6
18	R (K)	60S ribosomal protein L36	polymer	105	12290.9	1	UniProt (Q9Y3U8) Pfam (PF01158)	Homo sapiens (human)	Large ribosomal subunit protein eL36
19	S (L)	60S ribosomal protein L27a	polymer	148	16604.5	1	UniProt (P46776) Pfam (PF00828)	Homo sapiens (human)	Large ribosomal subunit protein uL15
20	T (M)	60S ribosomal protein L37	polymer	97	11111.0	1	UniProt (P61927) Pfam (PF01907)	Homo sapiens (human)	Large ribosomal subunit protein eL37
21	U (N)	60S ribosomal protein L11	polymer	178	20288.5	1	UniProt (P62913) Pfam (PF00281) Pfam (PF00673)	Homo sapiens (human)	Large ribosomal subunit protein uL5
22	V (O)	60S ribosomal protein L38	polymer	70	8238.9	1	UniProt (P63173) Pfam (PF01781)	Homo sapiens (human)	Large ribosomal subunit protein eL38
23	W (P)	60S ribosomal protein L39	polymer	51	6426.8	1	UniProt (P62891) Pfam (PF00832)	Homo sapiens (human)	Large ribosomal subunit protein eL39
24	X (Q)	60S ribosomal protein L13	polymer	211	24321.7	1	UniProt (P26373) Pfam (PF01294)	Homo sapiens (human)	Large ribosomal subunit protein eL13
25	Y (S)	60S ribosomal protein L14	polymer	215	23485.0	1	UniProt (P50914) Pfam (PF01929)	Homo sapiens (human)	Large ribosomal subunit protein eL14
26	Z (U)	60S ribosomal protein L15	polymer	204	24207.3	1	UniProt (P61313) Pfam (PF00827)	Homo sapiens (human)	Large ribosomal subunit protein eL15
27	AA (V)	60S ribosomal protein L13a	polymer	203	23633.4	1	UniProt (P40429) Pfam (PF00572)	Homo sapiens (human)	Large ribosomal subunit protein uL13
28	BA (X)	60S ribosomal protein L37a	polymer	92	10299.4	1	UniProt (P61513) Pfam (PF01780)	Homo sapiens (human)	Large ribosomal subunit protein eL43
29	CA (Y)	60S ribosomal protein L17	polymer	184	21443.2	1	UniProt (P18621) Pfam (PF00237)	Homo sapiens (human)	Large ribosomal subunit protein uL22
30	DA (Z)	60S ribosomal protein L18	polymer	188	21687.7	1	UniProt (Q07020) Pfam (PF17135)	Homo sapiens (human)	Large ribosomal subunit protein eL18
31	EA (a)	60S ribosomal protein L19	polymer	196	23535.3	1	UniProt (P84098) Pfam (PF01280) Pfam (PF25476)	Homo sapiens (human)	Large ribosomal subunit protein eL19
32	FA (b)	60S ribosomal protein L18a	polymer	176	20808.5	1	UniProt (Q02543) Pfam (PF01775)	Homo sapiens (human)	Large ribosomal subunit protein eL20
33	GA (c)	60S ribosomal protein L21	polymer	160	18610.0	1	UniProt (P46778) Pfam (PF01157)	Homo sapiens (human)	Large ribosomal subunit protein eL21
34	HA (d)	60S ribosomal protein L22	polymer	128	14813.0	1	UniProt (P35268) Pfam (PF01776)	Homo sapiens (human)	Large ribosomal subunit protein eL22
35	IA (e)	60S ribosomal protein L23	polymer	140	14892.5	1	UniProt (P62829) Pfam (PF00238)	Homo sapiens (human)	Large ribosomal subunit protein uL14
36	JA (g)	60S ribosomal protein L23a	polymer	156	17740.2	1	UniProt (P62750) Pfam (PF03939) Pfam (PF00276)	Homo sapiens (human)	Large ribosomal subunit protein uL23
37	KA (h)	60S ribosomal protein L26	polymer	145	17303.4	1	UniProt (P61254) Pfam (PF16906) Pfam (PF00467)	Homo sapiens (human)	Large ribosomal subunit protein uL24
38	LA (i)	60S ribosomal protein L27	polymer	136	15835.8	1	UniProt (P61353) Pfam (PF00467) Pfam (PF01777)	Homo sapiens (human)	Large ribosomal subunit protein eL27
39	MA (j)	60S ribosomal protein L31	polymer	125	14494.9	1	UniProt (P62899) Pfam (PF01198)	Homo sapiens (human)	Large ribosomal subunit protein eL31
40	NA (k)	60S ribosomal protein L32	polymer	135	15898.9	1	UniProt (P62910) Pfam (PF01655)	Homo sapiens (human)	Large ribosomal subunit protein eL32
41	OA (l)	60S ribosomal protein L28	polymer	137	15784.6	1	UniProt (P46779) Pfam (PF01778)	Homo sapiens (human)	Large ribosomal subunit protein eL28
42	PA (m)	60S ribosomal protein L8	polymer	257	28088.9	1	UniProt (P62917) Pfam (PF00181) Pfam (PF03947)	Homo sapiens (human)	Large ribosomal subunit protein uL2
43	QA (n)	60S ribosomal protein L35a	polymer	110	12564.7	1	UniProt (P18077) Pfam (PF01247)	Homo sapiens (human)	Large ribosomal subunit protein eL33
44	RA (o)	60S ribosomal protein L6	polymer	288	32810.2	1	UniProt (Q02878) Pfam (PF03868) Pfam (PF01159)	Homo sapiens (human)	Large ribosomal subunit protein eL6
45	SA (p)	60S ribosomal protein L7	polymer	248	29291.0	1	UniProt (P18124) Pfam (PF08079) Pfam (PF00327)	Homo sapiens (human)	Large ribosomal subunit protein uL30
46	TA (r)	60S ribosomal protein L5	polymer	297	34426.8	1	UniProt (P46777) Pfam (PF17144) Pfam (PF14204)	Homo sapiens (human)	Large ribosomal subunit protein uL18
47	UA (z)	Protein LLP homolog	polymer	129	15268.4	1	UniProt (Q9BRT6) Pfam (PF10169)	Homo sapiens (human)	Protein LAPS18-like
48	VA (A)	G Protein Nucleolar 2	polymer	731	83796.1	1	UniProt (Q13823) Pfam (PF01926) Pfam (PF08153)	Homo sapiens (human)	Autoantigen NGP-1
49	WA (R)	Translation machinery-associated protein 16	polymer	203	23912.4	1	UniProt (Q96EY4) Pfam (PF11176)	Homo sapiens (human)
50	XA (J)	mRNA turnover protein 4 homolog	polymer	239	27602.5	1	UniProt (Q9UKD2) Pfam (PF00466) Pfam (PF17777)	Homo sapiens (human)	Ribosome assembly factor MRTO4
51	YA (y)	60S ribosomal protein L12	polymer	165	17847.6	1	UniProt (P30050) Pfam (PF03946) Pfam (PF00298)	Homo sapiens (human)	Large ribosomal subunit protein uL11
52	ZA (v)	Pescadillo homolog	polymer	588	68114.7	1	UniProt (O00541) Pfam (PF06732) Pfam (PF16589)	Homo sapiens (human)
53	AB (8)	5.8S rRNA	polymer	156	50157.7	1	GenBank (KY962518)	Homo sapiens (human)
54	BB (W)	60S ribosomal protein L36a	polymer	106	12477.0	1	UniProt (P83881) Pfam (PF00935)	Homo sapiens (human)	Large ribosomal subunit protein eL42
55	CB (T)	Leydig cell tumor 10 kDa protein homolog	polymer	99	10605.7	1	UniProt (Q9UNZ5) Pfam (PF09495)	Homo sapiens (human)
56	DB (s)	Ribosome biogenesis protein NSA2 homolog	polymer	260	30136.7	1	UniProt (O95478) Pfam (PF01201)	Homo sapiens (human)	Hairy cell leukemia protein 1,TGF-beta-inducible nuclear protein 1
57	EB (w)	Ribosome biogenesis protein NOP53	polymer	478	54498.4	1	UniProt (Q9NZM5) Pfam (PF07767)	Homo sapiens (human)	Glioma tumor suppressor candidate region gene 2 protein,Protein interacting with carboxyl terminus 1,PICT-1,p60
58	FB (x)	Internal Transcribed Spacer 2	polymer	60	11720.7	1		Homo sapiens (human)
59	GB (A)	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	1	Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537)
60	HB (A)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG) PubChem (888)
61	IB (A)	POTASSIUM ION	non-polymer		39.1	1	Chemie (K) PubChem (813)

Contents of the asymmetric unit

Polymers	Number of chains	58
	Total formula weight	3091655.5
Non-Polymers*	Number of molecules	3
	Total formula weight	506.6
All*	Total formula weight	3092162.1

*Water molecules are not included.