8IN0
Structure of the Keap1 Kelch domain in complex with PGAM5-derived peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Kelch-like ECH-associated protein 1 | polymer | 345 | 38302.0 | 1 | UniProt (Q9Z2X8) Pfam (PF01344) | Mus musculus (house mouse) | Cytosolic inhibitor of Nrf2,INrf2 |
| 2 | B (B) | PGAM5 12-mer peptide | polymer | 12 | 1403.6 | 1 | UniProt (by SIFTS) (Q96HS1) | Homo | |
| 3 | C, D, E, F (A) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 220 | Chemie (HOH) |
Sequence modifications
A: 309 - 624 (UniProt: Q9Z2X8)
| PDB | External Database | Details |
|---|---|---|
| Met 291 | - | initiating methionine |
| Met 292 | - | expression tag |
| Gly 293 | - | expression tag |
| His 294 | - | expression tag |
| His 295 | - | expression tag |
| His 296 | - | expression tag |
| His 297 | - | expression tag |
| His 298 | - | expression tag |
| His 299 | - | expression tag |
| Glu 300 | - | expression tag |
| Asn 301 | - | expression tag |
| Leu 302 | - | expression tag |
| Tyr 303 | - | expression tag |
| Phe 304 | - | expression tag |
| Gln 305 | - | expression tag |
| Gly 306 | - | expression tag |
| His 307 | - | expression tag |
| Met 308 | - | expression tag |
| Arg 625 | - | expression tag |
| Lys 626 | - | expression tag |
| Gln 627 | - | expression tag |
| Ile 628 | - | expression tag |
| Asp 629 | - | expression tag |
| Gln 630 | - | expression tag |
| Gln 631 | - | expression tag |
| Asn 632 | - | expression tag |
| Cys 633 | - | expression tag |
| Thr 634 | - | expression tag |
| Cys 635 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 39705.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 384.3 | |
| All* | Total formula weight | 40089.8 |
