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8IME

Human cGAS catalytic domain bound with baicalin

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BCyclic GMP-AMP synthasepolymer36642759.32UniProt (Q8N884)
Pfam (PF03281)
Pfam (PF20266)
In PDB
Homo sapiens (human)cGAMP synthase,cGAS,h-cGAS,2'3'-cGAMP synthase,Mab-21 domain-containing protein 1
2A, B5,6-dihydroxy-4-oxo-2-phenyl-4H-chromen-7-yl beta-D-glucopyranosiduronic acidnon-polymer446.42Chemie (0XE)
3A, BZINC IONnon-polymer65.42Chemie (ZN)
4waterwater18.016Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight85518.5
Non-Polymers*Number of molecules4
Total formula weight1023.5
All*Total formula weight86542.1
*Water molecules are not included.

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PDB entries from 2024-06-12

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