8IM6

Crystal structure of HCoV 229E main protease in complex with PF07304814

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	3C-like proteinase	polymer	299	32771.2	2	UniProt (P0C6X1) Pfam (PF05409)	Human coronavirus 229E	3CL-PRO,3CLp,M-PRO,nsp5,p34
2	C, D (A, B)	[(3~{S})-3-[[(2~{S})-2-[(4-methoxy-1~{H}-indol-2-yl)carbonylamino]-4-methyl-pentanoyl]amino]-2-oxidanylidene-4-[(3~{R})-2-oxidanylidene-3,4-dihydropyrrol-3-yl]butyl] dihydrogen phosphate	non-polymer		552.5	2	Chemie (80I)
3	E, F (A, B)	water	water		18.0	151	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	65542.4
Non-Polymers*	Number of molecules	2
	Total formula weight	1105.0
All*	Total formula weight	66647.5

*Water molecules are not included.