8IKM
Trans complex of phospho parkin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | E3 ubiquitin-protein ligase parkin | polymer | 247 | 27508.4 | 1 | UniProt (O60260) Pfam (PF17976) Pfam (PF17978) | Homo sapiens (human) | Parkin,Parkin RBR E3 ubiquitin-protein ligase,Parkinson juvenile disease protein 2,Parkinson disease protein 2 |
| 2 | B (B) | Ubiquitin | polymer | 75 | 8599.8 | 1 | UniProt (P62987) Pfam (PF00240) | Homo sapiens (human) | |
| 3 | C (C) | E3 ubiquitin-protein ligase parkin | polymer | 146 | 16093.9 | 1 | UniProt (O60260) Pfam (PF00240) | Homo sapiens (human) | Parkin,Parkin RBR E3 ubiquitin-protein ligase,Parkinson juvenile disease protein 2,Parkinson disease protein 2 |
| 4 | D, E, F, G, H... (A) | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) | |||
| 5 | J (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | K (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 7 | L, M, N (A, B, C) | water | water | 18.0 | 96 | Chemie (HOH) |
Sequence modifications
A: 141 - 382 (UniProt: O60260)
C: 1 - 140 (UniProt: O60260)
| PDB | External Database | Details |
|---|---|---|
| Cys 347 | Gln 347 | engineered mutation |
| Asn 383 | - | expression tag |
| Leu 384 | - | expression tag |
| Tyr 385 | - | expression tag |
| Phe 386 | - | expression tag |
| Gln 387 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Leu 141 | - | expression tag |
| Glu 142 | - | expression tag |
| Val 143 | - | expression tag |
| Leu 144 | - | expression tag |
| Phe 145 | - | expression tag |
| Gln 146 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 52202.1 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 590.7 | |
| All* | Total formula weight | 52792.8 |
