8IKE
Transcription factors LMX1a mutant-R199A homeobox domain complex with Wnt1 promoter
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA (5'-D(*CP*CP*AP*TP*AP*TP*TP*TP*AP*AP*TP*CP*TP*TP*C)-3') | polymer | 15 | 4493.9 | 1 | Homo sapiens | ||
| 2 | B (B) | DNA (5'-D(*GP*GP*AP*AP*GP*AP*TP*TP*AP*AP*AP*TP*AP*TP*G)-3') | polymer | 15 | 4681.1 | 1 | Homo sapiens | ||
| 3 | C (C) | LMX1A factor | polymer | 60 | 6975.2 | 1 | UniProt (A0A7K7QDL0) Pfam (PF00046) UniProt (by SIFTS) (Q8TE12) | Homo sapiens (human) | |
| 4 | D, E, F (A, B, C) | water | water | 18.0 | 23 | Chemie (HOH) |
Sequence modifications
C: 197 - 256 (UniProt: A0A7K7QDL0)
| PDB | External Database | Details |
|---|---|---|
| Ala 199 | Arg 198 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 16150.3 | |
| All* | Total formula weight | 16150.3 |
