8IIZ
Crystal structure of MBP fused GAS41 YEATS domain in complex with H3K27ac peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Maltodextrin-binding protein,YEATS domain-containing protein 4 | polymer | 514 | 57212.9 | 1 | UniProt (C3SHQ8) UniProt (O95619) Pfam (PF01547) Pfam (PF03366) UniProt (by SIFTS) (P0AEX9) In PDB | Escherichia coli | Glioma-amplified sequence 41,Gas41,NuMA-binding protein 1,NuBI-1,NuBI1 |
| 2 | B, C | Histone H3.1 | polymer | 32 | 3388.9 | 2 | UniProt (P68431) In PDB | Homo sapiens | Histone H3/a,Histone H3/b,Histone H3/c,Histone H3/d,Histone H3/f,Histone H3/h,Histone H3/i,Histone H3/j,Histone H3/k,Histone H3/l |
| 3 | D | alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | branched | 342.3 | 1 | In PDB BIRD (PRD_900001) GlyTouCan (G07411ON) | |||
| 4 | A | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 5 | water | water | 18.0 | 104 | Chemie (HOH) |
Sequence modifications
A: -351 - 14 (UniProt: C3SHQ8)
A: 19 - 159 (UniProt: O95619)
| PDB | External Database | Details |
|---|---|---|
| Gly -354 | - | expression tag |
| Ser -353 | - | expression tag |
| Met -352 | - | expression tag |
| Ala -270 | Asp 108 | engineered mutation |
| Ala -269 | Lys 109 | engineered mutation |
| Ala -180 | Glu 198 | engineered mutation |
| Ala -179 | Asn 199 | engineered mutation |
| Ala -113 | Lys 265 | engineered mutation |
| Asn 15 | - | linker |
| Ala 16 | - | linker |
| Ala 17 | - | linker |
| Ala 18 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 63990.8 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 342.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 276.3 | |
| All* | Total formula weight | 64609.4 |
