8IIY
Crystal structure of MBP fused GAS41 YEATS domain in complex with H3K14ac peptide
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Maltodextrin-binding protein,YEATS domain-containing protein 4 | polymer | 514 | 57212.9 | 1 | UniProt (C3SHQ8) UniProt (O95619) Pfam (PF01547) Pfam (PF03366) UniProt (by SIFTS) (P0AEX9) In PDB | Escherichia coli | Glioma-amplified sequence 41,Gas41,NuMA-binding protein 1,NuBI-1,NuBI1 |
2 | B, C | Histone H3.1 | polymer | 19 | 2118.4 | 2 | UniProt (P68431) In PDB | Homo sapiens | Histone H3/a,Histone H3/b,Histone H3/c,Histone H3/d,Histone H3/f,Histone H3/h,Histone H3/i,Histone H3/j,Histone H3/k,Histone H3/l |
3 | D | alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | branched | 666.6 | 1 | In PDB BIRD (PRD_900010) GlyTouCan (G87171PZ) | |||
4 | A | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
5 | water | water | 18.0 | 145 | Chemie (HOH) |
Sequence modifications
A: -351 - 14 (UniProt: C3SHQ8)
A: 19 - 159 (UniProt: O95619)
PDB | External Database | Details |
---|---|---|
Gly -354 | - | expression tag |
Ser -353 | - | expression tag |
Met -352 | - | expression tag |
Ala -270 | Asp 108 | engineered mutation |
Ala -269 | Lys 109 | engineered mutation |
Ala -180 | Glu 198 | engineered mutation |
Ala -179 | Asn 199 | engineered mutation |
Ala -113 | Lys 265 | engineered mutation |
Asn 15 | - | linker |
Ala 16 | - | linker |
Ala 17 | - | linker |
Ala 18 | - | linker |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 61449.8 | |
Branched | Number of molecules | 1 |
Total formula weight | 666.6 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 184.2 | |
All* | Total formula weight | 62300.6 |