8IHT

Rpd3S bound to the nucleosome

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, E	Histone H3	polymer	135	15332.0	2	UniProt (A0A310TTQ1) Pfam (PF00125) In PDB	Xenopus laevis (African clawed frog)
2	B, F	Histone H4	polymer	102	11263.2	2	UniProt (A0A8J1LTD2) Pfam (PF15511) In PDB	Xenopus laevis (African clawed frog)
3	C, G	Histone H2A	polymer	129	13978.2	2	UniProt (Q6AZJ8) Pfam (PF00125) Pfam (PF16211) In PDB	Xenopus laevis (African clawed frog)
4	D, H	Histone H2B	polymer	122	13524.8	2	UniProt (A0A8J0U496) Pfam (PF00125) In PDB	Xenopus laevis (African clawed frog)
5	I	DNA (164-MER)	polymer	164	50291.0	1		Xenopus laevis (African clawed frog)
6	J	DNA (165-MER)	polymer	165	51256.6	1		Xenopus laevis (African clawed frog)
7	M, O	RCO1 isoform 1	polymer	684	78951.3	2	UniProt (A0A8H4BXB0) Pfam (PF00628) In PDB	Saccharomyces cerevisiae (brewer's yeast)
8	N, P	Chromatin modification-related protein EAF3	polymer	401	45266.4	2	UniProt (A0A8H4F719) Pfam (PF11717) Pfam (PF05712) In PDB	Saccharomyces cerevisiae (brewer's yeast)
9	K	Transcriptional regulatory protein SIN3	polymer	1536	175047.3	1	UniProt (P22579) Pfam (PF16879) Pfam (PF02671) Pfam (PF08295) In PDB	Saccharomyces cerevisiae (brewer's yeast)
10	L	Histone deacetylase RPD3	polymer	433	48962.0	1	UniProt (P32561) Pfam (PF00850) In PDB	Saccharomyces cerevisiae (brewer's yeast)	Transcriptional regulatory protein RPD3
11	L	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
12	L	CALCIUM ION	non-polymer		40.1	1	Chemie (CA)

Sequence modifications

A, E: 1 - 135 (UniProt: A0A310TTQ1)

PDB	External Database	Details
Ala 110	Cys 111	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	16
	Total formula weight	682188.7
Non-Polymers*	Number of molecules	2
	Total formula weight	105.5
All*	Total formula weight	682294.2

*Water molecules are not included.