8IF1

Complex structure of HLA2402 with recognizing SARS-CoV-2 Y453F epitope NYNYLFRLF

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, G	MHC class I antigen	polymer	308	35437.1	3	UniProt (D9UAY1) Pfam (PF00129) Pfam (PF07654) In PDB	Homo sapiens (human)
2	B, D, H	Beta-2-microglobulin	polymer	101	11994.4	3	UniProt (P61769) Pfam (PF07654) In PDB	Homo sapiens (human)
3	E, F, I	Spike protein S1	polymer	9	1250.4	3	UniProt (P0DTC2) In PDB	Severe acute respiratory syndrome coronavirus 2
4		water	water		18.0	4	Chemie (HOH)

Sequence modifications

A, C, G: 1 - 276 (UniProt: D9UAY1)

PDB	External Database	Details
Met -4	-	initiating methionine
Asn -3	-	expression tag
Ser -2	-	expression tag
Val -1	-	expression tag
Asp 0	-	expression tag
Gly 277	-	expression tag
Ser 278	-	expression tag
Gly 279	-	expression tag
Leu 280	-	expression tag
Asn 281	-	expression tag
Asp 282	-	expression tag
Ile 283	-	expression tag
Phe 284	-	expression tag
Glu 285	-	expression tag
Ala 286	-	expression tag
Gln 287	-	expression tag
Lys 288	-	expression tag
Ile 289	-	expression tag
Glu 290	-	expression tag
Trp 291	-	expression tag
His 292	-	expression tag
Ala 293	-	expression tag
Ala 294	-	expression tag
Ala 295	-	expression tag
Leu 296	-	expression tag
Glu 297	-	expression tag
His 298	-	expression tag
His 299	-	expression tag
His 300	-	expression tag
His 301	-	expression tag
His 302	-	expression tag
His 303	-	expression tag

B, D, H: 1 - 99 (UniProt: P61769)

PDB	External Database	Details
Asp -1	-	expression tag
Met 0	-	expression tag

E, F, I: 1 - 9 (UniProt: P0DTC2)

PDB	External Database	Details
Phe 6	Tyr 453	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	9
	Total formula weight	146045.8
All*	Total formula weight	146045.8

*Water molecules are not included.