8IDM

Crystal structure of nanobody VHH-227 with nanobody VHH-T71 and MERS-CoV RBD

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	B	VHH-227	polymer	135	14769.2	1		Camelus dromedarius
2	A	VHH-T71	polymer	136	14863.2	1		Camelus dromedarius
3	D	Spike protein S1	polymer	229	25258.4	1	UniProt (R9UQ53) Pfam (PF09408) UniProt (by SIFTS) (K9N5Q8) In PDB	Middle East respiratory syndrome-related coronavirus	S glycoprotein,E2,Peplomer protein
4	C	alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		367.3	1	In PDB GlyTouCan (G86851RC)
5	E	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
6	D	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)

Sequence modifications

D: 367 - 589 (UniProt: R9UQ53)

PDB	External Database	Details
His 590	-	expression tag
His 591	-	expression tag
His 592	-	expression tag
His 593	-	expression tag
His 594	-	expression tag
His 595	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	54890.8
Branched	Number of molecules	2
	Total formula weight	791.8
Non-Polymers*	Number of molecules	1
	Total formula weight	221.2
All*	Total formula weight	55903.8

*Water molecules are not included.