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8ID9

Cryo-EM structure of the eicosapentaenoic acid bound GPR120-Gi complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(B)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1polymer33937285.71UniProt (P62873)
Pfam (PF00400)
Homo sapiens (human)
2B
(Y)
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2polymer717861.11UniProt (P59768)
Pfam (PF00631)
Homo sapiens (human)G gamma-I
3C
(S)
scFv16polymer28530363.01Homo sapiens (human)
4D
(A)
Guanine nucleotide-binding protein G(i) subunit alpha-1polymer35440415.01UniProt (P63096)
Pfam (PF00503)
Homo sapiens (human)Adenylate cyclase-inhibiting G alpha protein
5E
(R)
Free fatty acid receptor 4polymer36140533.21UniProt (Q5NUL3)
Pfam (PF00001)
Homo sapiens (human)G-protein coupled receptor 120,G-protein coupled receptor 129,G-protein coupled receptor GT01,G-protein coupled receptor PGR4,Omega-3 fatty acid receptor 1
6F
(R)
5,8,11,14,17-EICOSAPENTAENOIC ACIDnon-polymer302.51Chemie (EPA)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight156458.2
Non-Polymers*Number of molecules1
Total formula weight302.5
All*Total formula weight156760.6
*Water molecules are not included.

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PDB entries from 2025-06-11

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