8IAS

Crystal structure of Streptococcus pneumoniae pyruvate kinase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Pyruvate kinase	polymer	521	56993.6	4	UniProt (Q8DQ84) Pfam (PF00224) Pfam (PF02887)	Streptococcus pneumoniae R6
2	E, F (B, D)	CITRIC ACID	non-polymer		192.1	2	Chemie (CIT)
3	G (D)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
4	H, I, J, K (A, B, C, D)	water	water		18.0	857	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 501 (UniProt: Q8DQ84)

PDB	External Database	Details
Met -19	-	initiating methionine
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	227974.4
Non-Polymers*	Number of molecules	3
	Total formula weight	476.3
All*	Total formula weight	228450.7

*Water molecules are not included.