8I7Z
The crystal structure of human abl1 kinase domain in complex with ABL1-B5
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Tyrosine-protein kinase ABL1 | polymer | 272 | 31659.1 | 2 | UniProt (P00519) Pfam (PF07714) | Homo sapiens (Human) | Abelson murine leukemia viral oncogene homolog 1,Abelson tyrosine-protein kinase 1,Proto-oncogene c-Abl,p150 |
| 2 | C, E (A, B) | 5-[3-(2-methoxy-5-oxidanyl-phenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-N,N-dimethyl-pyridine-3-carboxamide | non-polymer | 388.4 | 2 | Chemie (6CI) | |||
| 3 | D (A) | BETA-ALANINE | non-polymer | 89.1 | 1 | Chemie (BAL) | |||
| 4 | F, G (A, B) | water | water | 18.0 | 273 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 63318.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 865.9 | |
| All* | Total formula weight | 64184.2 |
